Shedding light on the cell biology of extracellular vesicles
G Van Niel, G d'Angelo, G Raposo - Nature reviews Molecular cell …, 2018 - nature.com
Extracellular vesicles are a heterogeneous group of cell-derived membranous structures
comprising exosomes and microvesicles, which originate from the endosomal system or …
comprising exosomes and microvesicles, which originate from the endosomal system or …
Disseminated intravascular coagulation
S Gando, M Levi, CH Toh - Nature reviews Disease primers, 2016 - nature.com
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by
widespread intravascular activation of coagulation that can be caused by infectious insults …
widespread intravascular activation of coagulation that can be caused by infectious insults …
A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles
TB Gandek, L van der Koog… - Advanced healthcare …, 2023 - Wiley Online Library
A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …
internalization in target cells. Two prominent examples of such drug delivery systems are …
Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases
A Ståhl, K Johansson, M Mossberg, R Kahn… - Pediatric …, 2019 - Springer
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
M Colombo, G Raposo, C Théry - Annual review of cell and …, 2014 - annualreviews.org
In the 1980s, exosomes were described as vesicles of endosomal origin secreted from
reticulocytes. Interest increased around these extracellular vesicles, as they appeared to …
reticulocytes. Interest increased around these extracellular vesicles, as they appeared to …
Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges
Extracellular vesicles (EVs) are small, lipid-bound particles containing nucleic acid and
protein cargo which are excreted from cells under a variety of normal and pathological …
protein cargo which are excreted from cells under a variety of normal and pathological …
Disseminated intravascular coagulation: an update on pathogenesis, diagnosis, and therapeutic strategies
C Papageorgiou, G Jourdi, E Adjambri… - Clinical and applied …, 2018 - journals.sagepub.com
Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome
characterized by widespread activation of coagulation leading to fibrin deposition in the …
characterized by widespread activation of coagulation leading to fibrin deposition in the …
Endothelial barrier dysfunction in septic shock
SM Opal, T Van Der Poll - Journal of internal medicine, 2015 - Wiley Online Library
The endothelium provides an essential and selective membrane barrier that regulates the
movement of water, solutes, gases, macromolecules and the cellular elements of the blood …
movement of water, solutes, gases, macromolecules and the cellular elements of the blood …
Microparticles in hemostasis and thrombosis
AP Owens III, N Mackman - Circulation research, 2011 - Am Heart Assoc
Blood contains microparticles (MPs) derived from a variety of cell types, including platelets,
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …
monocytes, and endothelial cells. In addition, tumors release MPs into the circulation. MPs …