Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …

It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Chemotherapeutic drugs frequently encounter multidrug resistance. ATP from mitochondria
helps overexpression of drug efflux pumps to induce multidrug resistance, so mitochondrial …

Background PEGylated polylactide (PLA) and poly (lactic-co-glycolic acid)(PLGA)
copolymers are biodegradable polyesters, widely employed in the last decades for the …

Background Lung cancer is the primary cause of cancer-related death worldwide. A redox-
sensitive nanocarrier system was developed for tumor-targeted drug delivery and sufficient …

Nanoparticles (NPs) are atomic clusters of crystalline or amorphous structure that possess
unique physical and chemical properties associated with a size range of between 1 and 100 …

The aim of this review was to describe the preferred charged nano-particles (CNPs) for
targeted delivery in tumor cells. Zeta Potential (ZP), which represents the surface charge of …

Cancer cells normally develop the ability to rewire or reprogram themselves to become
resistant to treatments that were previously effective. Despite progress in understanding …

Undoubtedly the applications of polymers are rapidly evolving. Technology is continually
changing and quickly advancing as polymers are needed to solve a variety of day-to-day …

This review aims to overview and critically analyses recent developments in achieving
tumour-specific delivery of anticancer agents, maximizing anticancer efficacy, and mitigating …