Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

The discovery of antibiotics has created a turning point in medical interventions to
pathogenic infections, but unfortunately, each discovery was consistently followed by the …

In today's modern era of medicine, macromolecular compounds such as proteins, peptides
and nucleic acids are dethroning small molecules as leading therapeutics. Given their …

Approximately 75% of all disease-relevant human proteins, including those involved in
intracellular protein–protein interactions (PPIs), are undruggable with the current drug …

The presence of cell and tissue barriers together with the low biomembrane permeability of
various therapeutics often hampers systemic drug distribution; thus, most of the available …

Anti-cancer peptides (ACPs) are a series of short peptides composed of 10–60 amino acids
that can inhibit tumour cell proliferation or migration, or suppress the formation of tumour …

Introduction The biological membranes as natural permeable barriers are required for
survival and function of living cells. However, these natural barriers could be a major …

Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

The rapid increase in drug-resistant infections has presented a serious challenge to
antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” …