In the United States, prostate cancer (CaP) remains the second leading cause of cancer
deaths in men. CaP is predominantly indolent at diagnosis, with a small fraction (25–30%) …

Recent studies demonstrating epigenetic and developmental sensitivity to early
environments, as exemplified by fields like the Developmental Origins of Health and …

Black men with prostate cancer have historically had worse outcomes than white men with
prostate cancer. The causes of this disparity in outcomes are multi-factorial, but a potential …

DNA methylation, as the most intensively studied epigenetic mark, regulates gene
expression in numerous biological processes including development, aging, and disease …

Abstract Background African Americans (AAs) in the United States are known to have a
higher incidence and mortality for Prostate Cancer (PCa). The drivers of this epidemiological …

Black and Hispanic cancer patients have a higher incidence of cancer mortality. Many
factors (eg, socioeconomic differences, insufficient access to healthcare) contribute to racial …

Prostate cancer (PCa) incidence, morbidity, and mortality rates are significantly impacted by
racial disparities. Despite innovative therapeutic approaches and advancements in …

This review focuses on the critical role of epigenetic modifications in solid tumor metastasis,
particularly in people of African ancestry. Epigenetic alterations, such as DNA methylation …

As the era of cancer genomics expands, disproportionate rates of prostate cancer incidence
and mortality by race have demonstrated increasing relevance in clinical settings. While …

Prostate cancer, bladder cancer, and renal cancers are major urogenital cancers. Of which,
prostate cancer is the most commonly diagnosed and second leading cause of cancer death …