Per-and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts
L Gaillard, R Barouki, E Blanc, X Coumoul… - Trends in Endocrinology …, 2024 - cell.com
The widespread use of per-and polyfluoroalkyl substances (PFASs), and their resistance to
degradation, renders human exposure to them inevitable. PFAS exposure disturbs …
degradation, renders human exposure to them inevitable. PFAS exposure disturbs …
Thyroid hormone biomonitoring: A review on their metabolism and machine-learning based analysis on effects of endocrine disrupting chemicals
S Chen, M Yu, Y Yao, Y Li, A He, Z Zhou… - Environment & …, 2024 - ACS Publications
The thyroid is an essential endocrine organ in human body, and thyroid hormones (THs) are
pivotal signaling molecules and mediators in various physiological processes. THs …
pivotal signaling molecules and mediators in various physiological processes. THs …
Short-chain per-and polyfluoralkyl substances (PFAS) effects on oxidative stress biomarkers in human liver, kidney, muscle, and microglia cell lines
ME Solan, CP Koperski, S Senthilkumar… - Environmental Research, 2023 - Elsevier
Long-chain per-and polyfluoralkyl substances (PFAS) are ubiquitous contaminants
implicated in the induction of intracellular reactive oxygen species (ROS), compromising …
implicated in the induction of intracellular reactive oxygen species (ROS), compromising …
[HTML][HTML] The contribution of PFAS to thyroid hormone-displacing activity in Dutch waters: A comparison between two in vitro bioassays with chemical analysis
JKH De Schepper, Y van Oorschot, RJ Jaspers… - Environment …, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are a group of xenobiotics that are widely
distributed throughout the aquatic environment. Many PFAS are possible thyroid hormone …
distributed throughout the aquatic environment. Many PFAS are possible thyroid hormone …
A co-twin control study of in utero exposure to poly-and perfluoroalkyl substances and associations with neonatal thyroid-stimulating hormone
L Hu, H Mei, X Cai, F Xiang, N Li, Z Huang… - Environmental …, 2023 - Elsevier
Research quantifying associations between early-life exposure to poly-and perfluoroalkyl
substances (PFAS) and neonatal thyroid hormone levels is limited and reports inconsistent …
substances (PFAS) and neonatal thyroid hormone levels is limited and reports inconsistent …
Changing the structure of PFOA and PFOS: a chemical industry strategy or a solution to avoid thyroid-disrupting effects?
F Coperchini, A Greco, M Rotondi - Journal of Endocrinological …, 2024 - Springer
Background The family of perfluoroalkyl and polyfluoroalkyl substances (PFAS) raised
concern for their proven bioaccumulation and persistence in the environment and animals …
concern for their proven bioaccumulation and persistence in the environment and animals …
A combinational threat of micro-and nano-plastics (MNPs) as potential emerging vectors for per-and polyfluoroalkyl substances (PFAS) to human health
SD Santhanam, K Ramamurthy, PS Priya… - Environmental …, 2024 - Springer
Micro-and nano-plastics (MNPs) and per-and polyfluoroalkyl substances (PFAS) are
prevalent in ecosystems due to their exceptional properties and widespread use, profoundly …
prevalent in ecosystems due to their exceptional properties and widespread use, profoundly …
[HTML][HTML] Associations between serum per-and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Y Xing, Z Li, J Wang, Y Qu, Q Hu, S Ji, X Chang… - Environment …, 2024 - Elsevier
Disruption of thyroid homeostasis has been indicated in human studies on the effects of per-
and polyfluoroalkyl substances (PFASs). However, limited research exists on this topic …
and polyfluoroalkyl substances (PFASs). However, limited research exists on this topic …
[HTML][HTML] The pollutant perfluorohexane sulfonate (PFHxS) reduces serum thyroxine but does not alter thyroid action in the postnatal rat brain
Known as “forever chemicals”, per-and polyfluoroalkyl substances (PFAS) are synthetic
compounds used in consumer goods but pose significant public health concerns, including …
compounds used in consumer goods but pose significant public health concerns, including …
[HTML][HTML] Adverse outcome pathway for the neurotoxicity of Per-and polyfluoroalkyl substances: A systematic review
Per-and polyfluoroalkyl substances (PFAS) are endocrine disruptors with unambiguous
neurotoxic effects. However, due to variability in experimental models, population …
neurotoxic effects. However, due to variability in experimental models, population …