The γ‐aminobutyric acid type A (GABAA) receptor represents an elementary switching
mechanism integral to the functioning of the central nervous system and a locus for the …

GABA A receptor channels mediate postsynaptic inhibition. The functional diversity of these
receptors rests on differences in subunit composition and on a large repertoire of subunits …

Abstract γ‐Aminobutyric acidA (GABAA) receptors in the mammalian central nervous system
(CNS) are members of a family of ligand‐gated ion channels consisting of heterooligomeric …

Congenital myoclonus is a widespread neurologic disorder characterized by
hyperexcitability, muscular spasticity and myoclonus associated with marked reduction in …

GABAA receptors have an age-adapted function in the brain. During early development,
they mediate excitatory effects resulting in activation of calcium sensitive signaling …

Mice homozygous for the spastic mutation (spa) suffer from a complex motor disorder
resulting from reduced CNS levels of the adult glycine receptor isoform CI~ RA, which is …

Screening of a genomic DNA library with a portion of the cDNA encoding the γ-aminobutyric
acid (GABA) receptor subunit rho 1 identified two distinct clones. DNA sequencing revealed …

The inhibitory glycine receptor is a ligand-gated ion channel protein that occurs in different
developmentally regulated isoforms in the mammalian central nervous system. Here, we …

cDNAs encoding three splice variants of the P2X2 receptor were isolated from rat
cerebellum. The first variant has a serine/proline-rich segment deleted from the …

Opioid and opioid-like receptors are activated by a variety of endogenous peptides including
[Met] enkephalin (met),[Leu] enkephalin (leu), β-endorphin (β-end), α-neodynorphin …