[HTML][HTML] Cyanobacterial Harmful Algal Bloom Toxin Microcystin and Increased Vibrio Occurrence as Climate-Change-Induced Biological Co-Stressors: Exposure and …

S Chatterjee, M More - Toxins, 2023 - mdpi.com
The effects of global warming are not limited to rising global temperatures and have set in
motion a complex chain of events contributing to climate change. A consequence of global …

A new identity of microcystins: Environmental endocrine disruptors? An evidence-based review

S Zhang, H Liu, X Du, X Chen, P Petlulu, Z Tian… - Science of The Total …, 2022 - Elsevier
Microcystins (MCs) are widely distributed cyanobacterial toxins in eutrophic waters. At
present, the endocrine-disrupting effects of MCs have been extensively studied, but whether …

Multi-omics analysis reveals the toxic mechanism of ammonia-enhanced Microcystis aeruginosa exposure causing liver fat deposition and muscle nutrient loss in …

K Ou-Yang, Y Kuang, H Yang, Y He, L Wang… - Journal of Hazardous …, 2024 - Elsevier
Microcystis aeruginosa and ammonia pollution are two important environmental stress
factors in water eutrophication. Herein, we simulated environmental conditions to investigate …

[HTML][HTML] Cyanotoxins increase cytotoxicity and promote nonalcoholic fatty liver disease progression by enhancing cell steatosis

S Niture, S Gadi, Q Qi, L Rios-Colon, S Khatiwada… - Toxins, 2023 - mdpi.com
Freshwater prokaryotic cyanobacteria within harmful algal blooms produce cyanotoxins
which are considered major pollutants in the aquatic system. Direct exposure to cyanotoxins …

Effects of acute exposure to microcystins on hypothalamic-pituitary-adrenal (HPA),-gonad (HPG) and-thyroid (HPT) axes of female rats

L Chen, T Shi, YT Wang, J He, X Zhao, YK Wang… - Science of The Total …, 2021 - Elsevier
Microcystins (MCs) are common, well-known cyanobacterial toxins that can affect health of
humans. Recently, it has been reported that MCs affect endocrine functions. In the present …

Prediction of Microcystis occurrences and analysis using machine learning in high-dimension, low-sample-size and imbalanced water quality data

M Mori, RG Flores, Y Suzuki, K Nukazawa, T Hiraoka… - Harmful Algae, 2022 - Elsevier
Abstract Machine learning, Deep learning, and water quality data have been used in recent
years to predict the outbreak of harmful algae, especially Microcystis, and analyze outbreak …

[HTML][HTML] Hepatic NLRP3-Derived Hsp70 Binding to TLR4 Mediates MASLD to MASH Progression upon Inhibition of PP2A by Harmful Algal Bloom Toxin Microcystin, a …

S Roy, P Saha, D Bose, A Trivedi, M More… - International journal of …, 2023 - mdpi.com
Harmful algal bloom toxin microcystin has been associated with metabolic dysfunction-
associated steatotic liver disease (MASLD) progression and hepatocellular carcinoma …

[HTML][HTML] Prior exposure to microcystin alters host gut resistome and is associated with dysregulated immune homeostasis in translatable mouse models

P Saha, D Bose, V Stebliankin, T Cickovski, RK Seth… - Scientific reports, 2022 - nature.com
A strong association between exposure to the common harmful algal bloom toxin
microcystin and the altered host gut microbiome has been shown. We tested the hypothesis …

Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are …

A Mondal, P Saha, D Bose, S Chatterjee, RK Seth… - Toxicology, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has been shown to be associated with extrahepatic
comorbidities including neuronal inflammation and Alzheimer's-like pathology …

Risk prediction of microcystins based on water quality surrogates: A case study in a eutrophicated urban river network

X He, H Wang, W Zhuang, D Liang, Y Ao - Environmental Pollution, 2021 - Elsevier
Microcystins (MCs), the toxic by-products from harmful algal bloom (HAB), have caused
world-wide concern due to their acute toxicity in freshwater ecosystems. Most studies on …