Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …

In the past two decades, research has underlined the potential of ultrasound and
microbubbles to enhance drug delivery. However, there is less consensus on the …

Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics
in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical-or …

Ultrasound-triggered drug delivery is now becoming a mature technology with first patients
enrolling in clinical trials. Having a clear overview of the field is complicated as it mixes …

Over the last decade, there has been a significant progress towards the development of
microbubbles as theranostics for a wide variety of biomedical applications. The unique …

Focused Ultrasound (FUS) in combination with gaseous microbubbles has emerged as a
potential new means of effective drug delivery to the brain. Recent research has shown that …

Malignant glioma is one of the most challenging central nervous system (CNS) diseases,
which is typically associated with high rates of recurrence and mortality. Current surgical …

The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

Drug delivery research employing micelles and nanoparticles has expanded in recent years.
Of particular interest is the use of these nanovehicles that deliver high concentrations of …

Although promising results are achieved in ultrasound mediated drug delivery, its underlying
biophysical mechanisms remain to be elucidated. Pore formation as well as endocytosis has …