Purpose As part of the American Association of Physicists in Medicine Working Group on
Stereotactic Body Radiotherapy investigating normal tissue complication probability (NTCP) …

A recent meeting was held on March 22, 2019, among the FDA, clinical scientists,
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …

Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …

Gliomas are the most common primary intracranial neoplasms, which cause significant
mortality and morbidity that is disproportionate to their relatively rare incidence. Many …

Pseudophenomena, that is, imaging alterations due to therapy rather than tumor evolution,
have an important impact on the management of glioma patients and the results of clinical …

Background Animal brain-tumor models have demonstrated a synergistic interaction
between radiation therapy and a ketogenic diet (KD). Metformin has in-vitro anti-cancer …

Cancer therapy-induced adverse effects on the brain are a major challenge in neuro-
oncology. Brain tissue necrosis (treatment necrosis [TN]) as a consequence of brain directed …

Abstract Type 2 diabetes (T2D) is associated with increased risk of Alzheimer's disease
(AD). There is evidence for impaired blood–brain barrier (BBB) in both diseases, but its role …

Magnetic resonance image guided radiation therapy (MRIgRT) is a relatively new
technology that has already shown outcomes benefits but that has not yet reached its clinical …

Opinion statement Intracranial stereotactic radiosurgery (SRS) is an effective and convenient
treatment for many brain conditions. Data regarding safety come mostly from retrospective …