The genetic landscape of classical myeloproliferative neoplasm (MPN) is in large part
elucidated. The MPN-restricted driver mutations, including those in JAK2, calreticulin …

Clonal hematopoiesis (CH) broadly describes the expansion of a clonal population of blood
cells with one or more somatic mutations. Individuals with CH are at greater risk for …

Understanding the genetic and nongenetic determinants of tumor protein 53 (TP53)-
mutation-driven clonal evolution and subsequent transformation is a crucial step toward the …

Myeloid malignancies, including acute myeloid leukaemia (AML), arise from the expansion
of haematopoietic stem and progenitor cells that acquire somatic mutations. Bulk molecular …

The classic Philadelphia chromosome–negative myeloproliferative neoplasms (MPN)
consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a …

Overview: Essential thrombocythemia is a Janus kinase 2 (JAK2) mutation-prevalent
myeloproliferative neoplasm characterized by clonal thrombocytosis; clinical course is often …

Abstract BCR:: ABL1-negative myeloproliferative neoplasms (MPNs) are clonal diseases
originating from a single hematopoietic stem cell that cause excessive production of mature …

Mature T-cell lymphomas, including peripheral T-cell lymphoma (PTCL) and extranodal
NK/T-cell lymphoma (NKTL), represent a heterogeneous group of non-Hodgkin lymphomas …

Survival prediction in essential thrombocythaemia (ET) and polycythaemia vera (PV) is
currently based on clinically‐derived variables; we examined the possibility of integrating …

Polycythemia vera (PV) is characterized by JAK2 and essential thrombocythemia (ET) by
JAK2, calreticulin (CALR), and myeloproliferative leukemia virus oncogene (MPL) mutations; …