[HTML][HTML] The role of microRNAs in mammalian fertility: From gametogenesis to embryo implantation

D Salilew-Wondim, S Gebremedhn, M Hoelker… - International journal of …, 2020 - mdpi.com
The genetic codes inscribed during two key developmental processes, namely
gametogenesis and embryogenesis, are believed to determine subsequent development …

Stem cell insights into human trophoblast lineage differentiation

TKJB Gamage, LW Chamley… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND The human placenta is vital for fetal development, yet little is understood
about how it forms successfully to ensure a healthy pregnancy or why this process is …

[HTML][HTML] Embryonic POU5F1 is required for expanded bovine blastocyst formation

BW Daigneault, S Rajput, GW Smith, PJ Ross - Scientific reports, 2018 - nature.com
POU5F1 is a transcription factor and master regulator of cell pluripotency with indispensable
roles in early embryo development and cell lineage specification. The role of embryonic …

Parallel evolution of male germline epigenetic poising and somatic development in animals

BJ Lesch, SJ Silber, JR McCarrey, DC Page - Nature genetics, 2016 - nature.com
Abstract Changes in gene regulation frequently underlie changes in morphology during
evolution, and differences in chromatin state have been linked with changes in anatomical …

[HTML][HTML] Dynamics of DNA methylation during early development of the preimplantation bovine embryo

KB Dobbs, M Rodriguez, MJ Sudano, MS Ortega… - PloS one, 2013 - journals.plos.org
There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …

Comparative intrauterine development and placental function of ART concepti: implications for human reproductive medicine and animal breeding

E Bloise, SK Feuer, PF Rinaudo - Human reproduction update, 2014 - academic.oup.com
BACKGROUND The number of children conceived using assisted reproductive technologies
(ART) has reached> 5 million worldwide and continues to increase. Although the great …

Induced pluripotent stem cells from farm animals

Y Su, J Zhu, S Salman, Y Tang - Journal of animal science, 2020 - academic.oup.com
The development of the induced pluripotent stem cells (iPSC s) technology has
revolutionized the world on the establishment of pluripotent stem cells (PSC s) across a …

Bovine lineage specification revealed by single-cell gene expression analysis from zygote to blastocyst

Q Wei, L Zhong, S Zhang, H Mu, J Xiang… - Biology of …, 2017 - academic.oup.com
Preimplantation embryos undergo zygotic genome activation and lineage specification
resulting in three distinct cell types in the late blastocyst. The molecular mechanisms …

NANOG is required to form the epiblast and maintain pluripotency in the bovine embryo

MS Ortega, AM Kelleher, E O'Neil… - Molecular …, 2020 - Wiley Online Library
During preimplantation development, the embryo undergoes two consecutive lineages
specifications. The first cell fate decision determines which cells give rise to the …

[HTML][HTML] Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

SG Byars, QQ Huang, LA Gray, A Bakshi, S Ripatti… - PLoS …, 2017 - journals.plos.org
Traditional genome-wide scans for positive selection have mainly uncovered selective
sweeps associated with monogenic traits. While selection on quantitative traits is much more …