Sporotrichosis, a fungal disease, is caused by exposure to soil that harbors Sporothrix
schenckii or through inhalation of fungal spores. Skin is the most frequently exposed organ …

Introduction Omavaloxolone, an NRF2 activator, recently became the first drug approved
specifically for the treatment of Friedreich ataxia (FRDA). This landmark achievement …

The modification of natural or semisynthetic triterpenoids with amines can be explored as a
promising strategy for improving their pharmacological properties. Here, we report the …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease associated with
aging, characterized by progressive cognitive impairment and memory loss. However …

Natural products have always played an important role in pharmacotherapy, helping to
control pathophysiological processes associated with human disease. Thus, natural …