Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

Antimicrobial resistance (AMR) is a serious threat to global public health. It increases
morbidity and mortality, and is associated with high economic costs due to its health care …

Intervertebral disc (IVD) degeneration is a major cause of low back pain, a prevalent and
chronic condition that has a striking effect on quality of life. Currently, no approved …

Clustered, regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated (Cas) genes, a diverse family of prokaryotic adaptive immune systems, have …

Anaerobic digestion (AD) of waste activated sludge (WAS) is an important bio-energy
strategy that has been hindered by low conversion efficiency. This paper presents a …

Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Here we report the development of a high throughput, all-solution phase, and isothermal
detection system for African Swine Fever Virus (ASFV). CRISPR-Cas12a programmed with a …

Nucleic acid detection technology is now widely used in scientific research and clinical
testing, such as infectious and genetic diseases screening, molecular diagnosis of tumors …

Rapid emergence of antibiotic-resistant bacteria has made it harder for us to combat
infectious diseases and to develop new antibiotics. The clustered regularly interspaced short …

Establishment of production platforms through prokaryotic engineering in microbial
organisms would be one of the most efficient means for chemicals, protein, and biofuels …