Although liver transplantation is a true success story, many patients still die awaiting an
organ. The increasing need for liver grafts therefore remains an unsolved challenge to the …

Biliary complications are the most frequent cause of morbidity, re-transplantation, and even
mortality after liver transplantation. In general, biliary leakage and anastomotic and non …

A decision to withdraw life-sustaining treatment (WLST) is derived by a conclusion that
further treatment will not enable a patient to survive or will not produce a functional outcome …

Ex situ dual hypothermic oxygenated machine perfusion (DHOPE) and normothermic
machine perfusion (NMP) of donor livers may have a complementary effect when applied …

Current machine perfusion technology permits livers to be preserved ex situ for short periods
to assess viability prior to transplant. Long-term normothermic perfusion of livers is an …

Ex situ normothermic machine perfusion (NMP) might minimize ischemia/reperfusion injury
(IRI) of liver grafts. In this study, 20 primary liver transplantation recipients of older grafts (≥ …

Abstract Purpose of Review The transplant community continues to look for ways to help
address the discordance between donor liver graft availability and patients on the liver …

Background Normothermic machine perfusion of the liver (NMP-L) is a novel technique that
preserves liver grafts under near-physiological conditions while maintaining their normal …

Objective: Normothermic machine perfusion (NMP) enables optimized ex-vivo preservation
of a donor liver in a normal physiologic state. The impact of this emerging technology on …

In the face of a critical organ shortage in the Western world, various strategies are employed
to expand the donor pool for orthotopic liver transplantation (OLT). Among them is the …