The gut microbiome's role in the development, maintenance, and outcomes of sepsis

MW Adelman, MH Woodworth, C Langelier, LM Busch… - Critical care, 2020 - Springer
The gut microbiome regulates a number of homeostatic mechanisms in the healthy host
including immune function and gut barrier protection. Loss of normal gut microbial structure …

Trends in human fecal carriage of extended-spectrum β-lactamases in the community: toward the globalization of CTX-M

PL Woerther, C Burdet, E Chachaty… - Clinical microbiology …, 2013 - Am Soc Microbiol
In the last 10 years, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E)
have become one of the main challenges for antibiotic treatment of enterobacterial …

ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug‐resistant Gram‐negative bacteria in hospitalized …

E Tacconelli, MA Cataldo, SJ Dancer… - Clinical Microbiology …, 2014 - Wiley Online Library
Healthcare‐associated infections due to multidrug‐resistant Gram‐negative bacteria (MDR‐
GNB) are a leading cause of morbidity and mortality worldwide. These evidence‐based …

Fecal microbiota transplantation in patients with blood disorders inhibits gut colonization with antibiotic-resistant bacteria: results of a prospective, single-center study

J Bilinski, P Grzesiowski, N Sorensen… - Clinical Infectious …, 2017 - academic.oup.com
Background Patients with blood disorders colonized with antibiotic-resistant bacteria (ARB)
are prone to systemic infections that are difficult to treat. Reintroduction of commensal …

[HTML][HTML] ESCMID-EUCIC clinical guidelines on decolonization of multidrug-resistant Gram-negative bacteria carriers

E Tacconelli, F Mazzaferri, AM de Smet… - Clinical microbiology …, 2019 - Elsevier
Scope The aim of these guidelines is to provide recommendations for decolonizing
regimens targeting multidrug-resistant Gram-negative bacteria (MDR-GNB) carriers in all …

[HTML][HTML] A 5-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae: a randomized clinical trial

BD Huttner, V De Lastours, M Wassenberg… - Clinical microbiology …, 2019 - Elsevier
Objectives Intestinal carriage with extended spectrum β-lactamase Enterobacteriaceae
(ESBL-E) and carbapenemase-producing Enterobacteriaceae (CPE) can persist for months …

Intestinal colonization with multidrug-resistant Enterobacterales: screening, epidemiology, clinical impact, and strategies to decolonize carriers

EI Campos-Madueno, M Moradi, Y Eddoubaji… - European Journal of …, 2023 - Springer
The clinical impact of infections due to extended-spectrum β-lactamase (ESBL)-and/or
carbapenemase-producing Enterobacterales (Ent) has reached dramatic levels worldwide …

The intestinal microbiota: impacts of antibiotics therapy, colonization resistance, and diseases

T Shah, Z Baloch, Z Shah, X Cui, X Xia - International journal of molecular …, 2021 - mdpi.com
Trillions of microbes exist in the human body, particularly the gastrointestinal tract,
coevolved with the host in a mutually beneficial relationship. The main role of the intestinal …

Natural history and decolonization strategies for ESBL/carbapenem-resistant Enterobacteriaceae carriage: systematic review and meta-analysis

H Bar-Yoseph, K Hussein, E Braun… - Journal of Antimicrobial …, 2016 - academic.oup.com
Background ESBL-producing Enterobacteriaceae and carbapenem-resistant
Enterobacteriaceae (CRE) are rapidly spreading worldwide. Their natural reservoir is …

Clinical pharmacokinetics and pharmacodynamics of colistin

N Grégoire, V Aranzana-Climent, S Magréault… - Clinical …, 2017 - Springer
In this review, we provide an updated summary on colistin pharmacokinetics and
pharmacodynamics. Colistin is an old molecule that is frequently used as last-line treatment …