The opioid epidemic, with its noticeable increase in opioid prescriptions and related misuse,
abuse and resultant deaths in the previous 12 years, is a particularly North American …

Guidelines now discourage opioid analgesics for chronic noncancer pain because the
benefits frequently do not outweigh the harms. We aimed to determine the proportion of …

With a focus on practical acute pain management in adults in the hospital setting, this book
provides health professionals with simple and practical information to help them manage …

Introduction: The consumption of opioids has increased globally since the 1990s. Previous
studies of global opioid consumption have concentrated on morphine alone or a subset of …

Objective This review systematically identified studies that estimated the prevalence of
prescription opioid use in Australia, assessed the prevalence estimates for bias and …

Background Opioid use has more than doubled over recent decades, and Denmark
occupies fifth place in the global ranking. These increases have been partly attributed to the …

Purpose Significant increases in opioid utilisation have been reported in many countries in
recent decades. This study investigated strong opioid prescribing in Irish General Medical …

Introduction Prescription opioid use in Australia has increased over the last 3 decades. The
majority of opioids are prescribed and dispensed in primary care, however, there are few …

Opioid use in the United States and in many parts of the world has reached epidemic
proportions. This has led to excess mortality as well as significant changes in the …

Background Escalation of pharmaceutical opioid use and harm in North America is well-
documented, with similar issues emerging in Australia. One response is the development of …