1, 2, 3‐Triazole hybrids as anticancer agents: A review

MM Alam - Archiv der Pharmazie, 2022 - Wiley Online Library
Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …

Recent advances in 1, 2, 3-and 1, 2, 4-triazole hybrids as antimicrobials and their SAR: A critical review

G Tian, Q Song, Z Liu, J Guo, S Cao, S Long - European Journal of …, 2023 - Elsevier
With the widespread use and sometimes even abuse of antibiotics, the problem of bacterial
resistance to antibiotics has become very serious, and it is posing a great threat to global …

Ramachary-Bressy-Wang [3+ 2] cycloaddition reaction: Synthesis of fully decorated 1, 2, 3-triazoles as potent anticancer and EGFR inhibitors

M Kumar, SK Nukala, NS Thirukovela… - Journal of Molecular …, 2022 - Elsevier
A general strategy was developed for the synthesis of new fully decorated 1, 2, 3-triazoles
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …

The antibacterial activity of 1, 2, 3-triazole-and 1, 2, 4-triazole-containing hybrids against Staphylococcus aureus: An updated review (2020-present)

J Li, J Zhang - Current Topics in Medicinal Chemistry, 2022 - ingentaconnect.com
Staphylococcus aureus (S. aureus), a prominent, highly contagious nosocomial and
community-acquired bacterial pathogen, can cause a broad spectrum of diseases. Antibiotic …

Synthesis of novel pyrido [2, 3-d] pyrimidine-thiazolidine-1, 2, 3-triazoles: Potent EGFR targeting anticancer agents

SR Bandi, R Kapavarapu, R Palabindela… - Journal of Molecular …, 2023 - Elsevier
In this study, we designed and synthesized a number of novel pyrido [2, 3-d] pyrimidine-
thiazolidine-1, 2, 3-triazole derivatives and investigated them in vitro for their inhibitory …

Benzothiazole-[1, 2, 3] triazolo [5, 1-a] isoindoles: Synthesis, anticancer activity, bioavailability and in silico studies against Gama-Tubulin protein

M Kumar, SK Nukala, M Ravinder, TM Krishna… - Journal of Molecular …, 2022 - Elsevier
We, herein, reported the CuI catalyzed synthesis of some novel fused benzothiazole-1, 2, 3-
triazole hybrids (5a-5o) in one-pot. The in vitro anticancer activity of these compounds …

Synthesis and biological evaluation of novel [1, 2, 3] triazolo-pyrrolo [1, 2-a] pyrido [4, 3-d] pyrimidines as EGFR targeting anticancer agents

SR Bandi, N Kavitha, SK Nukala… - Journal of Molecular …, 2023 - Elsevier
Herein, we synthesized some new fused [1, 2, 3] triazolo-pyrrolo [1, 2-a] pyrido [4, 3-d]
pyrimidines via click chemistry followed by carbon-carbon bond coupling as key approach …

A simple work-up-free, solvent-free approach to novel amino acid linked 1, 4-disubstituted 1, 2, 3-triazoles as potent antituberculosis agents

A Garg, D Borah, P Trivedi, D Gogoi, AK Chaliha… - ACS …, 2020 - ACS Publications
An efficient, green strategy for synthesis of 1, 4-disubstituted-1, 2, 3-triazole has been
developed using 1, 8-diazabicyclo [5.4. 0] undec-7-ene (DBU) acetate ionic liquid (200 μL) …

Design, synthesis and evaluation of novel 1, 2, 4-triazole derivatives as promising anticancer agents

L Emami, S Sadeghian, A Mojaddami, S Khabnadideh… - BMC chemistry, 2022 - Springer
Herein, we reported the synthesis of nineteen novel 1, 2, 4-triazole derivatives including 1, 3-
diphenyl-2-(1H-1, 2, 4-triazol-1-yl) propan-1-ones (7a-e), 1-(1, 3-diphenylpropan-2-yl)-1 H-1 …

1, 2, 3-triazole derivatives with anti-breast cancer potential

X Wu, J Wang, S Xia, S Cheng… - Current Topics in …, 2022 - ingentaconnect.com
Breast cancer is one of the most prevalent malignant diseases, and one of the main causes
of mortality among women across the world. Despite advances in chemotherapy, drug …