Macrophages: Their role, activation and polarization in pulmonary diseases

S Arora, K Dev, B Agarwal, P Das, MA Syed - Immunobiology, 2018 - Elsevier
Macrophages, circulating in the blood or concatenated into different organs and tissues
constitute the first barrier against any disease. They are foremost controllers of both innate …

Targeting cell signaling in allergic asthma

SS Athari - Signal transduction and targeted therapy, 2019 - nature.com
Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …

Spotlight on microRNAs in allergy and asthma

J Weidner, S Bartel, A Kılıç, UM Zissler, H Renz… - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

L Vojtech, S Woo, S Hughes, C Levy… - Nucleic acids …, 2014 - academic.oup.com
Semen contains relatively ill-defined regulatory components that likely aid fertilization, but
which could also interfere with defense against infection. Each ejaculate contains trillions of …

Extracellular vesicles: novel communicators in lung diseases

A Mohan, S Agarwal, M Clauss, NS Britt… - Respiratory research, 2020 - Springer
The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

MicroRNA-mediated regulation of T helper cell differentiation and plasticity

D Baumjohann, KM Ansel - Nature Reviews Immunology, 2013 - nature.com
Abstract CD4+ T helper (TH) cells regulate appropriate cellular and humoral immune
responses to a wide range of pathogens and are central to the success of vaccines …

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

B Levänen, NR Bhakta, PT Paredes, R Barbeau… - Journal of Allergy and …, 2013 - Elsevier
BACKGROUND: Asthma is characterized by increased airway narrowing in response to
nonspecific stimuli. The disorder is influenced by both environmental and genetic factors …

Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma

RP Panganiban, Y Wang, J Howrylak… - Journal of Allergy and …, 2016 - Elsevier
Background MicroRNAs (miRNAs) are emerging as important regulatory molecules that
might be involved in the pathogenesis of various diseases. Circulating miRNAs might be …

Genetics and epigenetics in allergic rhinitis

BY Choi, M Han, JW Kwak, TH Kim - Genes, 2021 - mdpi.com
The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis

R Gandhi, B Healy, T Gholipour, S Egorova… - Annals of …, 2013 - Wiley Online Library
Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate
gene expression. Because they are stable in serum, they are being developed as …