Advances of nanotechnology for intracerebral hemorrhage therapy

J Wang, T Wang, M Fang, Z Wang, W Xu… - … in Bioengineering and …, 2023 - frontiersin.org
Intracerebral hemorrhage (ICH), the most devastating subtype of stoke, is of high mortality at
5 years and even those survivors usually would suffer permanent disabilities. Fortunately …

Tissue Compliance and Intracranial Pressure Responses to Large Intracerebral Hemorrhage in Young and Aged Spontaneously Hypertensive Rats

CM Wilkinson, ACJ Kalisvaart, TFC Kung… - …, 2024 - Am Heart Assoc
BACKGROUND: After a large intracerebral hemorrhage (ICH), the hematoma and swelling
cause intracranial pressure (ICP) to increase, sometimes causing brain herniation and …

Relationship between edema and intracranial pressure following intracerebral hemorrhage in rat

ACJ Kalisvaart, NA Bahr, F Colbourne - Frontiers in Stroke, 2023 - frontiersin.org
Elevated intracranial pressure (ICP) is a potentially fatal consequence of intracerebral
hemorrhage (ICH). As the mass of the hematoma and regional edema builds, ICP rises and …

“Baihui”(DU20)‐penetrating “Qubin”(GB7) acupuncture on blood–brain barrier integrity in rat intracerebral hemorrhage models via the RhoA/ROCK II/MLC 2 signaling …

C Zhang, J Zheng, X Yu, B Kuang, X Dai… - Animal Models and …, 2024 - Wiley Online Library
Abstract Background Blocking the RhoA/ROCK II/MLC 2 (Ras homolog gene family member
A/Rho kinase II/myosin light chain 2) signaling pathway can initiate neuroprotective …

Structural and molecular characterization of astrocyte and vasculature connectivity in the mouse hippocampus and cortex

C Lorin, R Guiet, N Chiaruttini, G Ambrosini, E Boci… - Glia - Wiley Online Library
The relation of astrocytic endfeet to the vasculature plays a key functional role in the neuro‐
glia‐vasculature unit. We characterize the spatial organization of astrocytes and the …

Efficacy of Rehabilitation in Translational Models of Intracerebral Hemorrhage

BA Fedor - 2024 - era.library.ualberta.ca
Intracerebral hemorrhage (ICH), a devastating stroke caused by the rupture of vasculature in
the brain, is responsible for< 20% of all strokes, yet accounts for a disproportionately high …