[HTML][HTML] In Vivo Imaging of Pancreatic Islet Grafts in Diabetes Treatment

DR Arifin, JWM Bulte - Frontiers in Endocrinology, 2021 - frontiersin.org
Transplantation of pancreatic islets has potential to offer life-long blood glucose
management in type I diabetes and severe type II diabetes without the need of exogenous …

Imaging in Type 1 Diabetes, Current Perspectives and Directions

J Tinklepaugh, NE Mamrak - Molecular Imaging and Biology, 2023 - Springer
Abstract Type 1 diabetes (T1D) is characterized by the autoimmune-mediated attack of
insulin-producing beta cells in the pancreas, leading to reliance on exogenous insulin to …

[HTML][HTML] Non-invasive in vivo imaging of porcine islet xenografts in a preclinical model with [68Ga]Ga-exendin-4

F Lindheimer, MJ Lindner, R Oos… - Frontiers in Nuclear …, 2023 - frontiersin.org
Background Islet xenotransplantation may be a therapeutic option in type 1 diabetes. Recent
advances in generating genetically modified source pigs offer advantages as immune …

Transgenic pigs expressing near infrared fluorescent protein—A novel tool for noninvasive imaging of islet xenotransplants

E Kemter, A Citro, L Wolf‐van Buerck, Y Qiu… - …, 2022 - Wiley Online Library
Background Islet xenotransplantation is a promising concept for beta‐cell replacement
therapy. Reporter genes for noninvasive monitoring of islet engraftment, graft mass changes …

[HTML][HTML] Identification and validation of a new peptide targeting pancreatic beta cells

Q Wang, L Zheng, K Wu, B Zhang - Molecules, 2022 - mdpi.com
Noninvasive targeted visualization of pancreatic beta cells or islets is becoming the focus of
molecular imaging application in diabetes and islet transplantation studies. In this study, we …

[PDF][PDF] Establishment of intraportal islet allotransplantation in a diabetic pig model

J Pilz - 2024 - edoc.ub.uni-muenchen.de
Type 1 diabetes (T1D) is a chronic autoimmune disease, which is characterized by the
destruction of insulin-producing beta cells in the pancreatic islets of Langerhans (reviewed …