Green chemistry in the synthesis of pharmaceuticals

S Kar, H Sanderson, K Roy, E Benfenati… - Chemical …, 2021 - ACS Publications
The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

Dual role of indoles derived from intestinal microbiota on human health

X Ye, H Li, K Anjum, X Zhong, S Miao, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Endogenous indole and its derivatives (indoles), considered as promising N-substituted
heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and …

New insights into gut-bacteria-derived indole and its derivatives in intestinal and liver diseases

X Li, B Zhang, Y Hu, Y Zhao - Frontiers in Pharmacology, 2021 - frontiersin.org
The interaction between host and microorganism widely affects the immune and metabolic
status. Indole and its derivatives are metabolites produced by the metabolism of tryptophan …

The role of oral microbiota in intra-oral halitosis

K Hampelska, MM Jaworska, ZŁ Babalska… - Journal of clinical …, 2020 - mdpi.com
Halitosis is a common ailment concerning 15% to 60% of the human population. Halitosis
can be divided into extra-oral halitosis (EOH) and intra-oral halitosis (IOH). The IOH is …

Targeting dietary and microbial tryptophan-indole metabolism as therapeutic approaches to colon cancer

M Wyatt, KL Greathouse - Nutrients, 2021 - mdpi.com
Tryptophan metabolism, via the kynurenine (Kyn) pathway, and microbial transformation of
tryptophan to indolic compounds are fundamental for host health; both of which are altered …

Environmental contamination by heterocyclic Polynuclear aromatic hydrocarbons and their microbial degradation

P Ghosh, S Mukherji - Bioresource Technology, 2021 - Elsevier
Heterocyclic polynuclear aromatic hydrocarbons (PAHs) have been detected in all
environmental matrices at few ppb to several ppm concentrations and they are characterized …

Fate, detection technologies and toxicity of heterocyclic PAHs in the aquatic and soil environments

P Ghosh, S Mukherji - Science of The Total Environment, 2023 - Elsevier
Heterocyclic polynuclear aromatic hydrocarbons (PAH) are characterized by higher
aqueous solubility and enhanced bioavailability due to presence of nitrogen, sulfur or …

An overview of microbial indigo-forming enzymes

AN Fabara, MW Fraaije - Applied Microbiology and Biotechnology, 2020 - Springer
Indigo is one of the oldest textile dyes and was originally prepared from plant material.
Nowadays, indigo is chemically synthesized at a large scale to satisfy the demand for dyeing …

A blueprint for transforming indigos to photoresponsive molecular tools

CY Huang, S Hecht - Chemistry–A European Journal, 2023 - Wiley Online Library
Indigo, one of the most ancient and abundant dyes in human history, has recently emerged
as a potential functional motif due to its intriguing photochemical properties. This review …

New octane booster molecules for modern gasoline composition

JH Badia, E Ramírez, R Bringué, F Cunill… - Energy & …, 2021 - ACS Publications
In the framework of reducing GHG emissions and accelerating the decarbonization of the
road transport sector, vehicle efficiency is a key factor for competitiveness. In this sense, the …