[HTML][HTML] Biophysics of tumor microenvironment and cancer metastasis-a mini review
The role of tumor microenvironment in cancer progression is gaining significant attention. It
is realized that cancer cells and the corresponding stroma co-evolve with time. Cancer cells …
is realized that cancer cells and the corresponding stroma co-evolve with time. Cancer cells …
A tense situation: forcing tumour progression
DT Butcher, T Alliston, VM Weaver - Nature Reviews Cancer, 2009 - nature.com
Cells within tissues are continuously exposed to physical forces including hydrostatic
pressure, shear stress, and compression and tension forces. Cells dynamically adapt to …
pressure, shear stress, and compression and tension forces. Cells dynamically adapt to …
[HTML][HTML] Mechanical stiffness controls dendritic cell metabolism and function
Stiffness in the tissue microenvironment changes in most diseases and immunological
conditions, but its direct influence on the immune system is poorly understood. Here, we …
conditions, but its direct influence on the immune system is poorly understood. Here, we …
Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration
I Acerbi, L Cassereau, I Dean, Q Shi, A Au… - Integrative …, 2015 - academic.oup.com
Tumors are stiff and data suggest that the extracellular matrix stiffening that correlates with
experimental mammary malignancy drives tumor invasion and metastasis. Nevertheless, the …
experimental mammary malignancy drives tumor invasion and metastasis. Nevertheless, the …
Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks
Injectable hydrogels can provide a scaffold for in situ tissue regrowth and regeneration, yet
gel degradation before tissue reformation limits the gels' ability to provide physical support …
gel degradation before tissue reformation limits the gels' ability to provide physical support …
A hybrid injectable hydrogel from hyperbranched PEG macromer as a stem cell delivery and retention platform for diabetic wound healing
The injectable hydrogel with desirable biocompatibility and tunable properties can improve
the efficacy of stem cell-based therapy. However, the development of injectable hydrogel …
the efficacy of stem cell-based therapy. However, the development of injectable hydrogel …
Indentation versus tensile measurements of Young's modulus for soft biological tissues
CT McKee, JA Last, P Russell… - Tissue Engineering Part B …, 2011 - liebertpub.com
In this review, we compare the reported values of Young's modulus (YM) obtained from
indentation and tensile deformations of soft biological tissues. When the method of …
indentation and tensile deformations of soft biological tissues. When the method of …
Medical ultrasound: imaging of soft tissue strain and elasticity
PNT Wells, HD Liang - Journal of the Royal Society …, 2011 - royalsocietypublishing.org
After X-radiography, ultrasound is now the most common of all the medical imaging
technologies. For millennia, manual palpation has been used to assist in diagnosis, but it is …
technologies. For millennia, manual palpation has been used to assist in diagnosis, but it is …
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
Most cancers in humans are large, measuring centimetres in diameter, and composed of
many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as …
many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as …
Imaging the elastic properties of tissue: the 20 year perspective
After 20 years of innovation in techniques that specifically image the biomechanical
properties of tissue, the evolution of elastographic imaging can be viewed from its infancy …
properties of tissue, the evolution of elastographic imaging can be viewed from its infancy …