Sex-Specific Dysconnective Brain Injuries and Neuropsychiatric Conditions such as Autism Spectrum Disorder Caused by Group B Streptococcus-Induced …

S Vancolen, T Ayash, MJ Allard, G Sébire - International Journal of …, 2023 - mdpi.com
Global health efforts have increased against infectious diseases, but issues persist with
pathogens like Group B Streptococcus (GBS). Preclinical studies have elaborated on the …

Cyclooxygenase (COX)-2 modulates Toxoplasma gondii infection, immune response and lipid droplets formation in human trophoblast cells and villous explants

G de Souza, RJ Silva, ICB Milián, AM Rosini… - Scientific Reports, 2021 - nature.com
Congenital toxoplasmosis is represented by the transplacental passage of Toxoplasma
gondii from the mother to the fetus. Our studies demonstrated that T. gondii developed …

Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages

S Du, H Huang, X Li, L Zhai, Q Zhu, K Zheng, X Song… - Chinese Medicine, 2020 - Springer
Background Apocynum venetum leaves are used as a kind of phytomedicine and the main
ingredient in some traditional Chinese medicine products for the relief of colitis. To …

Phytochemical profiling of antimicrobial and potential antioxidant plant: Nepeta cataria

A Nadeem, H Shahzad, B Ahmed, T Muntean… - Frontiers in Plant …, 2022 - frontiersin.org
Traditional and phytochemical studies have confirmed the richness and diversity of
medicinal plants such as Nepeta cataria (N. cataria), but more studies are needed to …

The changes in bacterial microbiome associated with immune disorder in allergic respiratory disease

J Lyu, F Kou, X Men, Y Liu, L Tang, S Wen - Microorganisms, 2022 - mdpi.com
Allergic respiratory disease is a worldwide and increasingly prevalent health problem. Many
researchers have identified complex changes in the microbiota of the respiratory and …

Uvaol improves the functioning of fibroblasts and endothelial cells and accelerates the healing of cutaneous wounds in mice

J Carmo, P Cavalcante-Araújo, J Silva, J Ferro… - Molecules, 2020 - mdpi.com
Uvaol is a natural pentacyclic triterpene that is widely found in olives and virgin olive oil,
exerting various pharmacological properties. However, information remains limited about …

Antineuroinflammatory Potential of Uvaol Transformation Products by Three Fungal Species

J Wang, W Liu, J Lu, M Zhu, Y Wu, W Pan… - Journal of Agricultural …, 2024 - ACS Publications
The prevalence of neurodegenerative diseases has increased in recent decades. Its exact
pathogenesis is not yet fully understood, and only a few drugs can be used clinically to …

Krüppel-like factor 6 (KLF6) requires its amino terminal domain to promote villous trophoblast cell fusion

AL Miranda, AC Racca, LT Kourdova, ML Rojas… - Placenta, 2022 - Elsevier
Introduction Villous cytotrophoblast (vCTB) cells fuse to generate and maintain the
syncytiotrophoblast layer required for placental development and function. Krüppel-like …

Biomarkers for a histological chorioamnionitis diagnosis in pregnant women with or without group B streptococcus infection: a case-control study

J Ren, Z Qiang, Y Li, J Zhang - BMC Pregnancy and Childbirth, 2021 - Springer
Background Chorioamnionitis may cause serious perinatal and neonatal adverse outcomes,
and group B streptococcus (GBS) is one of the most common bacteria isolated from human …

Uvaol ameliorates lipid deposition in hyperlipidemic hepatocytes by suppressing protein-tyrosine phosphatase 1B/ER stress signaling

HJ Gwon, YH Chung, W Cho, SW Choi… - Biochemical and …, 2024 - Elsevier
Uvaol (UV), a pentacyclic triterpene found in olives and virgin olive oil, is known for its anti-
inflammatory and antioxidant effects in various disease models. While olive oil is reported to …