Regulatory DNA elements can control the expression of distant genes via physical
interactions. Here we present a cost-effective methodology and computational analysis …

Since the discovery of induced pluripotent stem cells (iPSCs), numerous approaches have
been explored to improve the original protocol, which is based on a two-dimensional (2D) …

Functional assay limitations are an emerging issue in characterizing human pluripotent stem
cells (PSCs). With rodent PSCs, chimera formation using pre-implantation embryos is the …

Regenerative medicine aims to replace lost cells and to restore damaged tissues and
organs by either tissue‐engineering approaches or stimulation of endogenous processes …

Biallelic mutations of the human RNU4ATAC gene, which codes for the minor spliceosomal
U4atac snRNA, cause the developmental disorder, MOPD I/TALS. To date, nine separate …

Several mouse pluripotent stem cell types have been established either from mouse
blastocysts and epiblasts. Among these, embryonic stem cells (ESCs) are considered to …

Consistent and robust manufacturing is essential for the translation of cell therapies, and the
utilisation automation throughout the manufacturing process may allow for improvements in …

Induced pluripotent stem (iPS) cells from somatic cells have great potential for regenerative
medicine. The efficiency in generation of iPS cells has been significantly improved in recent …

Induced pluripotent stem cell (iPSC) technology has provided researchers with a unique tool
to derive disease-specific stem cells for the study and possible treatment of degenerative …

The hypothesis was tested that the pluripotency of the inner cell mass (ICM) of the bovine
embryo is enhanced by the glycogen synthase kinase-3β inhibitor CHIR99021 and the …