The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …

Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …

Aquaporins are protein channels that facilitate the flow of water across plasma cell
membranes in response to osmotic gradients. This review summarizes the evidence that …

Aquaporins (AQPs) are a family of transmembrane water channel proteins, which were
initially characterized as a novel protein family that plays a vital role in transcellular and …

Three aquaporins are expressed in the brain. AQP4, the predominant brain water channel,
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …

Abstract Background The aquaporins (AQPs) are a family of 13 small hydrophobic integral
transmembrane water channel proteins involved in transcellular and transepithelial water …

Acutely increased intracranial pressure (ICP) is a life-threatening neurosurgical emergency.
Optimal management strategy is selected according to the causative process. Typical …

The blood-brain barrier (BBB) selectively controls the homeostasis of the Central Nervous
System (CNS) environment by the specific structural and biochemical features of the …

The water-selective channel protein aquaporin-4 (AQP4) contributes to the migration and
proliferation of gliomas, and to their resistance to therapy. Here we show, in glioma cell …