Renewed discussion about whether or not adult neurogenesis exists in the human
hippocampus, and the nature and strength of the supporting evidence, has been reignited …

Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …

Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis
contribute to plasticity and unique brain functions in rodents, and are dysregulated in …

The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …

Adult hippocampal neurogenesis plays a critical role in memory and emotion processing,
and this process is dynamically regulated by neural circuit activity. However, it remains …

The field of epitranscriptomics examines the recently deciphered form of gene expression
regulation that is mediated by type-and site-specific RNA modifications. Similarly to the role …

Adult somatic stem cells in various organs maintain homeostatic tissue regeneration and
enhance plasticity. Since its initial discovery five decades ago, investigations of adult …

Standard treatment of primary and metastatic brain tumours includes high-dose
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …

The notion of exploiting the regenerative potential of the human brain in physiological aging
or neurological diseases represents a particularly attractive alternative to conventional …