Monoclonal antibodies in cancer immunotherapy

I Kimiz-Gebologlu, S Gulce-Iz, C Biray-Avci - Molecular biology reports, 2018 - Springer
Nowadays, in cancer treatments, immunotherapy which can be classified as a cancer type
specific therapy is more popular than non-specific therapy methods such as surgery …

FDA-approved drugs for hematological malignancies—the last decade review

A Sochacka-Ćwikła, M Mączyński, A Regiec - Cancers, 2021 - mdpi.com
Simple Summary Hematological malignancies are diseases involving the abnormal
production of blood cells. The aim of the study is to collect comprehensive information on …

Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma

E Zah, E Nam, V Bhuvan, U Tran, BY Ji… - Nature …, 2020 - nature.com
Chimeric antigen receptor (CAR)-T cell therapy has shown remarkable clinical efficacy
against B-cell malignancies, yet marked vulnerability to antigen escape and tumor relapse …

Infectious complications of biological and small molecule targeted immunomodulatory therapies

JS Davis, D Ferreira, E Paige, C Gedye… - Clinical microbiology …, 2020 - Am Soc Microbiol
The past 2 decades have seen a revolution in our approach to therapeutic
immunosuppression. We have moved from relying on broadly active traditional medications …

Long-lived plasma cells in mice and men

SF Brynjolfsson, L Persson Berg… - Frontiers in …, 2018 - frontiersin.org
Even though more than 30 years have passed since the eradication of smallpox, high titers
of smallpox-specific antibodies are still detected in the blood of subjects vaccinated in …

New strategies using antibody combinations to increase cancer treatment effectiveness

I Corraliza-Gorjón, B Somovilla-Crespo… - Frontiers in …, 2017 - frontiersin.org
Antibodies have proven their high value in antitumor therapy over the last two decades.
They are currently being used as the first-choice to treat some of the most frequent …

Restoring natural killer cell immunity against multiple myeloma in the era of new drugs

G Pittari, L Vago, M Festuccia, C Bonini… - Frontiers in …, 2017 - frontiersin.org
Transformed plasma cells in multiple myeloma (MM) are susceptible to natural killer (NK)
cell-mediated killing via engagement of tumor ligands for NK activating receptors or “missing …

The future of myeloma precision medicine: integrating the compendium of known drug resistance mechanisms with emerging tumor profiling technologies

T Harding, L Baughn, S Kumar, B Van Ness - Leukemia, 2019 - nature.com
Multiple myeloma (MM) is a hematologic malignancy that is considered mostly incurable in
large part due to the inability of standard of care therapies to overcome refractory disease …

Proteomic alteration in the progression of multiple myeloma: A comprehensive review

NH Ismail, A Mussa, MJ Al-Khreisat, S Mohamed Yusoff… - Diagnostics, 2023 - mdpi.com
Multiple myeloma (MM) is an incurable hematologic malignancy. Most MM patients are
diagnosed at a late stage because the early symptoms of the disease can be uncertain and …

[HTML][HTML] The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of multiple myeloma

N Shah, J Aiello, DE Avigan, JG Berdeja… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Outcomes in multiple myeloma (MM) have improved dramatically in the last two decades
with the advent of novel therapies including immunomodulatory agents (IMiDs), proteasome …