DNA functional materials assembled from branched DNA: design, synthesis, and applications
Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …
alternative perspective, DNA is a versatile molecular building-block for the construction of …
A hitchhiker's guide to click-chemistry with nucleic acids
NZ Fantoni, AH El-Sagheer, T Brown - Chemical Reviews, 2021 - ACS Publications
Click chemistry is an immensely powerful technique for the fast and efficient covalent
conjugation of molecular entities. Its broad scope has positively impacted on multiple …
conjugation of molecular entities. Its broad scope has positively impacted on multiple …
Supramolecular DNA assembly
CK McLaughlin, GD Hamblin, HF Sleiman - Chemical Society Reviews, 2011 - pubs.rsc.org
The powerful self-assembly features of DNA make it a unique template to finely organize
and control matter on the nanometre scale. While DNA alone offers a high degree of fidelity …
and control matter on the nanometre scale. While DNA alone offers a high degree of fidelity …
Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage
We demonstrate temperature-controlled encapsulation and release of the enzyme
horseradish peroxidase using a preassembled and covalently closed three-dimensional …
horseradish peroxidase using a preassembled and covalently closed three-dimensional …
Multiphoton absorption in amyloid protein fibres
Fibrillization of peptides leads to the formation of amyloid fibres, which, when in large
aggregates, are responsible for diseases such as Alzheimer's and Parkinson's,,,. Here, we …
aggregates, are responsible for diseases such as Alzheimer's and Parkinson's,,,. Here, we …
Tension induces a base-paired overstretched DNA conformation
N Bosaeus, AH El-Sagheer, T Brown… - Proceedings of the …, 2012 - National Acad Sciences
Mixed-sequence DNA molecules undergo mechanical overstretching by approximately 70%
at 60–70 pN. Since its initial discovery 15 y ago, a debate has arisen as to whether the …
at 60–70 pN. Since its initial discovery 15 y ago, a debate has arisen as to whether the …
DNA polyhedra with T-linkage
X Li, C Zhang, C Hao, C Tian, G Wang, C Mao - ACS nano, 2012 - ACS Publications
This paper reports a strategy for DNA self-assembly. Cross-over-based DNA nanomotifs are
held together by T-junctions instead of commonly used sticky-end cohesion. We have …
held together by T-junctions instead of commonly used sticky-end cohesion. We have …
Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures
G Clavé, G Chatelain, A Filoramo… - Organic & …, 2014 - pubs.rsc.org
The interest in the functionalization of oligonucleotides with organic molecules has grown
considerably over the last decade. In this work, we report on the synthesis and …
considerably over the last decade. In this work, we report on the synthesis and …
A New Modular Approach to Nanoassembly: Stable and Addressable DNA Nanoconstructs via Orthogonal Click Chemistries
SR Gerrard, C Hardiman, M Shelbourne… - Acs Nano, 2012 - ACS Publications
Thermodynamic instability is a problem when assembling and purifying complex DNA
nanostructures formed by hybridization alone. To address this issue, we have used …
nanostructures formed by hybridization alone. To address this issue, we have used …
Proximity ligation-responsive catalytic hairpin assembly-guided DNA dendrimers for synergistically amplified electrochemical biosensing
Y Liao, J Gao, Y Zhang, Y Zhou, R Yuan… - Sensors and Actuators B …, 2020 - Elsevier
Herein, we report a specific and sensitive electrochemical aptasensor through the proximity
ligation-responsive catalytic hairpin assembly (PLCHA) to guide the construction of …
ligation-responsive catalytic hairpin assembly (PLCHA) to guide the construction of …