DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Click chemistry is an immensely powerful technique for the fast and efficient covalent
conjugation of molecular entities. Its broad scope has positively impacted on multiple …

The powerful self-assembly features of DNA make it a unique template to finely organize
and control matter on the nanometre scale. While DNA alone offers a high degree of fidelity …

We demonstrate temperature-controlled encapsulation and release of the enzyme
horseradish peroxidase using a preassembled and covalently closed three-dimensional …

Fibrillization of peptides leads to the formation of amyloid fibres, which, when in large
aggregates, are responsible for diseases such as Alzheimer's and Parkinson's,,,. Here, we …

Mixed-sequence DNA molecules undergo mechanical overstretching by approximately 70%
at 60–70 pN. Since its initial discovery 15 y ago, a debate has arisen as to whether the …

This paper reports a strategy for DNA self-assembly. Cross-over-based DNA nanomotifs are
held together by T-junctions instead of commonly used sticky-end cohesion. We have …

The interest in the functionalization of oligonucleotides with organic molecules has grown
considerably over the last decade. In this work, we report on the synthesis and …

Thermodynamic instability is a problem when assembling and purifying complex DNA
nanostructures formed by hybridization alone. To address this issue, we have used …

Herein, we report a specific and sensitive electrochemical aptasensor through the proximity
ligation-responsive catalytic hairpin assembly (PLCHA) to guide the construction of …