Viral encephalitis

RJ Whitley - New England Journal of Medicine, 1990 - Mass Medical Soc
VIRAL infections of the central nervous system (CNS) have attracted the attention of
historians and physicians for millennia. 1, 2 With the exception of herpes simplex …

Ligands for glutamate receptors: design and therapeutic prospects

H Bräuner-Osborne, J Egebjerg… - Journal of medicinal …, 2000 - ACS Publications
(S)-Glutamic acid (Glu), which is the main excitatory neurotransmitter in the central nervous
system (CNS), and other excitatory amino acids (EAAs) operate through four different …

Overexpression of nef as a marker for restricted HIV‐1 infection of astrocytes in postmortem pediatric central nervous tissues

Y Saito, LR Sharer, LG Epstein, J Michaels, M Mintz… - Neurology, 1994 - AAN Enterprises
In previous studies, using polymerase chain reaction amplification of HIV-1 genes directly
from pathologic tissues of children who died with AIDS encephalopathy, we showed that the …

Epidemiology of human immunodeficiency virus encephalopathy in the United States

RS Janssen, OC Nwanyanwu, RM Selik… - Neurology, 1992 - AAN Enterprises
To investigate the epidemiology of human immunodeficiency virus (HIV) encephalopathy,
we analyzed cases of acquired immunodeficiency syndrome (AIDS) reported to the Centers …

[HTML][HTML] CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

J Hesselgesser, M Halks-Miller, V DelVecchio… - Current Biology, 1997 - cell.com
Background: Chemokines are a family of protiens that chemoattract and activate immune
cells by interacting with specific receptors on the surface of their targets. We have shown …

Cognitive function and neurodevelopmental outcomes in HIV-infected children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the …

T Puthanakit, J Ananworanich… - The Pediatric …, 2013 - journals.lww.com
Background: We previously reported similar AIDS-free survival at 3 years in children who
were> 1 year old initiating antiretroviral therapy (ART) and randomized to early versus …

[图书][B] Mental retardation: Nature, cause, and management

GS Baroff, JG Olley - 2014 - api.taylorfrancis.com
Mental Retardation, now in the third edition, was hailed as a classic when it was first
published in the 1970's. This edition provides up-to-date material on the major dimensions …

Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms

LG Epstein, HE Gendelman - Annals of Neurology: Official …, 1993 - Wiley Online Library
Human immunodeficiency virus type 1 (HIV‐1) infection of the central nervous system is
associated with characteristic virological, clinical, and neuropathological findings in adults …

Impact of the HIV/AIDS epidemic on the neurodevelopment of preschool-aged children in Kinshasa, Democratic Republic of the Congo

A Van Rie, A Mupuala, A Dow - Pediatrics, 2008 - publications.aap.org
OBJECTIVES. Pediatric HIV infection is a growing problem in most regions of the world.
Data on the effects of HIV on the neurodevelopment of children in resource-poor settings are …

Neurologic and neurodevelopmental manifestations of pediatric HIV/AIDS: a global perspective

A Van Rie, PR Harrington, A Dow… - European journal of …, 2007 - Elsevier
Neurodevelopmental abnormalities associated with HIV infection have been described
since the first reports of pediatric AIDS in the 1980s. Before antiretroviral therapy (ART) …