The essential medicinal chemistry of curcumin: miniperspective
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …
Curcumin and colorectal cancer: An update and current perspective on this natural medicine
W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …
[HTML][HTML] Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review
Hydrogels have emerged as a versatile platform for a numerous biomedical application due
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
Anti-cancer effects of green tea epigallocatchin-3-gallate and coffee chlorogenic acid
Tea and coffee are consumed worldwide and epidemiological and clinical studies have
shown their health beneficial effects, including anti-cancer effects. Epigallocatechin gallate …
shown their health beneficial effects, including anti-cancer effects. Epigallocatechin gallate …
Curcumin—from molecule to biological function
T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
Multitargeting by curcumin as revealed by molecular interaction studies
Covering: up to early 2011 Curcumin (diferuloylmethane), the active ingredient in turmeric
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …
The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions
A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
Cancer chemoprevention by dietary polyphenols: promising role for epigenetics
Epigenetics refers to heritable changes that are not encoded in the DNA sequence itself, but
play an important role in the control of gene expression. In mammals, epigenetic …
play an important role in the control of gene expression. In mammals, epigenetic …