These guidelines describe a comprehensive strategy to optimize oxygenation, airway
management, and tracheal intubation in critically ill patients, in all hospital locations. They …

Objective: To update the 2002 version of “Clinical practice guidelines for sustained
neuromuscular blockade in the adult critically ill patient.” Design: A Task Force comprising …

Sedative medications are widely used in intensive care unit (ICU) patients. Structured
assessment of sedation and agitation is useful to titrate sedative medications and to …

Background Continuous infusions of sedative drugs in the intensive care unit may prolong
the duration of mechanical ventilation, prolong the length of stay in the intensive care unit …

Objective: Extubation failure is associated with a poor prognosis, but the respective roles for
reintubation per se and underlying disease severity remain unclear. Our objectives were to …

Objective: To compare a practice of protocol-directed sedation during mechanical ventilation
implemented by nurses with traditional non-protocol-directed sedation administration …

Extubation failure, defined as the need for reinstitution of ventilatory support within 24 to 72
hours of planned endotracheal tube removal, occurs in 2 to 25% of extubated patients. The …

Unplanned extubation is a major complication of translaryngeal intubation, but its impact on
mortality, duration of mechanical ventilation (MV), length of intensive care unit (ICU) and …

BACKGROUND: In this study, we updated the state of knowledge on unplanned tracheal
extubations in the intensive care unit. We focused on the following topics: incidence, risk …

Health-care professionals (HCPs) can provide protocol-based care that has a measurable
impact on critically ill patients beyond their liberation from mechanical ventilation (MV) …