Cachexia is the involuntary loss of muscle and adipose tissue that strongly affects mortality
and treatment efficacy in patients with cancer or chronic inflammatory disease. Currently, no …

Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …

Generating reactive oxygen species (ROS) is necessary for both physiology and pathology.
An imbalance between endogenous oxidants and antioxidants causes oxidative stress …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Under normal conditions, inflammation is a protective and physiological response to various
harmful stimuli. However, in several chronic debilitating disorders, such as chronic kidney …

Chronic kidney disease (CKD) is a debilitating pathology with various causal factors,
culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation …

Cardiovascular disease and infections are directly or indirectly associated with an altered
immune response, which leads to a high incidence of morbidity and mortality, and together …

Results Over a median follow-up time of 6.3 years, 899 participants reached the composite
end point of≥ 50% decline in eGFR from baseline or onset of ESRD. Elevated plasma …

Protein-energy wasting (PEW), a term proposed by the International Society of Renal
Nutrition and Metabolism (ISRNM), refers to the multiple nutritional and catabolic alterations …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …