Defining the relationship between COPD and CVD: what are the implications for clinical practice?

AD Morgan, R Zakeri, JK Quint - Therapeutic advances in …, 2018 - journals.sagepub.com
Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic
obstructive pulmonary disease (COPD). CVDs are common in people with COPD, and their …

Cardiovascular disease in COPD: mechanisms

JD Maclay, W MacNee - Chest, 2013 - Elsevier
It is now well established that cardiovascular disease contributes significantly to both
morbidity and mortality in COPD. Shared risk factors for cardiovascular disease and COPD …

A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays

Y Ni, BJHM Rosier, EA van Aalen… - Nature …, 2021 - nature.com
Heterogeneous immunoassays such as ELISA have become indispensable in modern
bioanalysis, yet translation into point-of-care assays is hindered by their dependence on …

Systemic inflammation in chronic obstructive pulmonary disease: a population-based study

F Garcia-Rio, M Miravitlles, JB Soriano, L Muñoz… - Respiratory …, 2010 - Springer
Background Elevated circulating levels of several inflammatory biomarkers have been
described in selected patient populations with COPD, although less is known about their …

The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity

H Watz, B Waschki, A Kirsten, KC Müller, G Kretschmar… - Chest, 2009 - Elsevier
Background The metabolic syndrome is a condition frequently found among individuals> 60
years of age. It predisposes affected individuals to systemic inflammation and physical …

Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk

NL Mills, JJ Miller, A Anand, SD Robinson, GA Frazer… - Thorax, 2008 - thorax.bmj.com
Rationale: Chronic obstructive pulmonary disease (COPD) is associated with a 2–3-fold
increase in the risk of ischaemic heart disease, stroke and sudden death. The mechanisms …

Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins

FJ Frost, H Petersen, K Tollestrup, B Skipper - Chest, 2007 - Elsevier
Background Published data on antiinflammatory and immunomodulatory effects of statins
suggest they may reduce mortality risks associated with an unchecked immune response to …

The value of blood cytokines and chemokines in assessing COPD

E Bradford, S Jacobson, J Varasteh, AP Comellas… - Respiratory …, 2017 - Springer
Background Blood biomarkers are increasingly used to stratify high risk chronic obstructive
pulmonary disease (COPD) patients; however, there are fewer studies that have …

Should we view chronic obstructive pulmonary disease differently after ECLIPSE?. A clinical perspective from the study team

J Vestbo, A Agusti, EFM Wouters, P Bakke… - American journal of …, 2014 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) seems to be a heterogeneous
disease with a variable course. Objectives: We wished to characterize the heterogeneity and …

The value of C-reactive protein as a marker of systemic inflammation in stable chronic obstructive pulmonary disease

F Karadag, S Kirdar, AB Karul, E Ceylan - European Journal of Internal …, 2008 - Elsevier
BACKGROUND: Systemic aspects of chronic obstructive pulmonary disease (COPD)
include oxidative stress and altered circulating levels of inflammatory mediators and acute …