In recent years there has been an increasing interest in the study of drug-excipient
interactions in pharmaceutical dosage forms. Maillard reaction is one of the most important …

Drug-excipient compatibility study (DECS) is one of the critical steps during pre-formulation
studies to select the appropriate excipient to obtain a stable formulation/dosage form. As …

Purpose: Assessment of drug substance and excipients compatibility is an important issue
during pre-formulation studies as well as the quality control of pharmaceutical dosage forms …

In this study, the incompatibility of doxepin in solid physical mixtures with lactose
(monohydrate and anhydrous) was investigated. The compatibility testing was made using …

In this study the stability of parenteral acyclovir (ACV) when diluted in dextrose (DEX) as
large volume intravenous fluid preparation (LVIF) was evaluated and the possible Maillard …

Background Following the introduction of new stability-indicating related substances
methods, an unknown impurity was observed in levothyroxine (LeMI) and liothyronine (LiMI) …

Background: Dry powder inhalers (DPIs) are dosage forms that are used via the pulmonary
route. Their formulations include two major parts; drug substance and carrier. For many …

In the present study, the compatibility between bisoprolol fumarate and selected excipients
(ascorbic acid, citric acid anhydrous, butylated hydroxyanisole, polyvinylpyrrolidone …

An unknown impurity was observed during stability studies of Gabapentin capsules. This
impurity has been identified, synthesized, isolated and characterized using modern …

Abstract Edivoxetine (LY2216684 HCl), although a chemically stable drug substance, has
shown the tendency to degrade in the presence of carbohydrates that are commonly used …