Red blood cell abnormalities as the mirror of SARS-CoV-2 disease severity: a pilot study

A Bouchla, AG Kriebardis, HT Georgatzakou… - Frontiers in …, 2022 - frontiersin.org
Purpose Unraveling the pathophysiology of COVID-19 disease is of crucial importance for
designing treatment. The purpose of this study is to investigate the effects of the disease on …

Effect of silica-based mesoporous nanomaterials on human blood cells

SP Fortis, A Batrinou, HT Georgatzakou… - Chemico-Biological …, 2024 - Elsevier
Different mesoporous nanomaterials (MSNs) are constantly being developed for a range of
therapeutic purposes, but they invariably interact with blood components and may cause …

[HTML][HTML] Beta thalassemia minor is a beneficial determinant of red blood cell storage lesion

VL Tzounakas, AT Anastasiadi, D Stefanoni… - …, 2022 - ncbi.nlm.nih.gov
Blood donor genetics and lifestyle affect the quality of red blood cell (RBC) storage.
Heterozygotes for beta thalassemia (bThal+) constitute a non-negligible proportion of blood …

Metabolic linkage and correlations to storage capacity in erythrocytes from glucose 6-phosphate dehydrogenase-deficient donors

JA Reisz, VL Tzounakas, T Nemkov… - Frontiers in …, 2018 - frontiersin.org
Objective In glucose 6-phosphate dehydrogenase (G6PD) deficiency, decreased NADPH
regeneration in the pentose phosphate pathway and subnormal levels of reduced …

Deciphering the relationship between free and vesicular hemoglobin in stored red blood cell units

VL Tzounakas, AT Anastasiadi, ME Lekka… - Frontiers in …, 2022 - frontiersin.org
Red blood cells (RBCs) release hemoglobin (Hb)-containing extracellular vesicles (EVs)
throughout their lifespan in the circulation, and especially during senescence, by spleen …

Whole blood storage in CPDA1 blood bags alters erythrocyte membrane proteome

AM Al-Thani, SC Voss, AS Al-Menhali… - Oxidative medicine …, 2018 - Wiley Online Library
Autologous blood transfusion (ABT) has been frequently abused in endurance sport and is
prohibited since the mid‐1980s by the International Olympic Committee. Apart from any …

Intelligent berberine-loaded erythrocytes attenuated inflammatory cytokine productions in macrophages

ZS Aghili, M Magnani, M Ghatrehsamani… - Scientific Reports, 2024 - nature.com
Erythrocytes are impressive tools for drug delivery, especially to macrophages. Therefore,
berberine was loaded into erythrocytes using both hypotonic pre-swelling and endocytosis …

Donor‐specific individuality of red blood cell performance during storage is partly a function of serum uric acid levels

VL Tzounakas, DG Karadimas, AT Anastasiadi… - …, 2018 - Wiley Online Library
BACKGROUND Previous investigations in leukoreduced units of red blood cells (RBCs) in
mannitol additive solution revealed the close association of uric acid (UA) levels in vivo with …

Effects of leukoreduction on storage lesions in whole blood and blood components of dogs

A Stefani, K Capello, A Carminato… - Journal of Veterinary …, 2021 - Wiley Online Library
Background Leukoreduction is a routine procedure in human transfusion medicine but is
uncommon in veterinary. Objectives To evaluate the effect of leukoreduction on the quality of …

The effect of blood viscosity on shear‐induced hemolysis using a magnetically levitated shearing device

JA Krisher, RA Malinauskas, SW Day - Artificial Organs, 2022 - Wiley Online Library
Introduction Blood contacting medical devices, including rotary blood pumps, can cause
shear‐induced blood damage that may lead to adverse effects in patients. Due in part to an …