Vulvovaginal candidosis

JD Sobel - The Lancet, 2007 - thelancet.com
Despite therapeutic advances, vulvovaginal candidosis remains a common problem
worldwide, affecting all strata of society. Understanding of anti-candida host defence …

Recurrent vulvovaginal candidiasis: an immunological perspective

D Rosati, M Bruno, M Jaeger, J Ten Oever, MG Netea - Microorganisms, 2020 - mdpi.com
Vulvovaginal candidiasis (VVC) is a widespread vaginal infection primarily caused by
Candida albicans. VVC affects up to 75% of women of childbearing age once in their life …

History and update on host defense against vaginal candidiasis

PL Fidel Jr - American journal of reproductive immunology, 2007 - Wiley Online Library
Vulvovaginal candidiasis (VVC), caused by Candida albicans, remains a significant problem
in women of childbearing age. While cell‐mediated immunity is considered the predominant …

Transcriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome

VM Bruno, AC Shetty, J Yano, PL Fidel Jr, MC Noverr… - MBio, 2015 - Am Soc Microbiol
Treatment of vulvovaginal candidiasis (VVC), caused most frequently by Candida albicans,
represents a significant unmet clinical need. C. albicans, as both a commensal and a …

Novel mechanism behind the immunopathogenesis of vulvovaginal candidiasis:“neutrophil anergy”

J Yano, BM Peters, MC Noverr… - Infection and immunity, 2018 - Am Soc Microbiol
For over 3 decades, investigators have studied the pathogenesis of vulvovaginal candidiasis
(VVC) and recurrent VVC (RVVC) through clinical studies and animal models. While there …

Vaginal yeast colonisation, prevalence of vaginitis, and associated local immunity in adolescents

MM Barousse, BJ Van Der Pol, D Fortenberry… - Sexually transmitted …, 2004 - sti.bmj.com
Objectives: To evaluate point prevalence vaginal yeast colonisation and symptomatic
vaginitis in middle adolescents and to identify relation of these yeast conditions with …

Vulvovaginal candidiasis: An overview of mycological, clinical, and immunological aspects

L Jafarzadeh, M Ranjbar, T Nazari… - Journal of Obstetrics …, 2022 - Wiley Online Library
Aim To provide an overview of clinical, immunological, and mycological aspects of
vulvovaginal candidiasis (VVC). Methods A literature search was conducted to find relevant …

Distinct protective host defenses against oral and vaginal candidiasis

PLF Jr - Medical mycology, 2002 - Taylor & Francis
Oral and vaginal candidiasis are the two most common forms of opportunistic fungal
infections. However, the prevalence of each can be quite variable depending on the immune …

History and new insights into host defense against vaginal candidiasis

PL Fidel - Trends in microbiology, 2004 - cell.com
Recurrent vulvovaginal candidiasis (RVVC), caused by Candida albicans, remains a
significant problem in women of childbearing age. Although cell-mediated immunity is …

Vaginal heparan sulfate linked to neutrophil dysfunction in the acute inflammatory response associated with experimental vulvovaginal candidiasis

J Yano, MC Noverr, PL Fidel Jr - MBio, 2017 - Am Soc Microbiol
Despite acute inflammation by polymorphonuclear neutrophils (PMNs) during vulvovaginal
candidiasis (VVC), clearance of Candida fails to occur. The purpose of this study was to …