Orofacial pain is a universal predicament, afflicting millions of individuals worldwide.
Research on the molecular mechanisms of orofacial pain has predominately focused on the …

Pulpitis causes significant changes in the peripheral nervous system, which induce
hyperalgesia. However, the relationship between neuronal activity and Nav1. 7 expression …

Background Dental pulp tissues are rich in pain‐related afferent nerve fibers, which
originate from primary sensory neurons in the trigeminal ganglion (TG). The mechanisms of …

Posttraumatic trigeminal neuropathy occurs as a consequence of an injury to the peripheral
branches of the trigeminal nerve. Examples include neuronal trauma during placement of …

Aims We have previously demonstrated that fructose supplementation (FS), given in a
scheme used for inducing metabolic syndrome (MS), elicited pain relief in the nitroglycerin …

The mechanism underlying allodynia/hyperalgesia caused by dental pulpitis has remained
enigmatic. This investigation endeavored to characterize the influence of the purinergic …

Aim To verify whether experimentally induced pulpitis activates the expression of transient
receptor potential vanilloid type 1 (TRPV1) and c‐Fos, both peripherally and centrally …

巨噬细胞作为机体免疫系统的重要组成部分, 可以在不同环境中被不同细胞分子诱导极化为M1
和M2 型巨噬细胞, 参与各种疾病的进展. 在炎症反应中, M1 型巨噬细胞主要作为促炎细胞 …

BACKGROUND: In commercial farming the shortening of piglet needle teeth is a common
but controversial and legally restricted practice due to its potential to induce pain and stress …

Objective: To establish a controlled pulp damage repair model in miniature pigs by using a
diode laser. Background: Laser is a novel kind of controllable energy, and it is widely used …