We have developed a general profile for the proteins of the TetR family of repressors. The
stretch that best defines the profile of this family is made up of 47 amino acid residues that …

While the biological functions of most of the secondary metabolites made by streptomycetes
are not known, it is inconceivable that they do not play an adaptive ecological role. The …

Small signalling molecules called γ-butyrolactones are mainly produced by Streptomyces
species in which they regulate antibiotic production and morphological differentiation. Their …

Streptomyces bacteria are the major source of antibiotics and other secondary metabolites.
Various environmental and physiological conditions affect the onset and level of production …

Streptomyces are Gram-positive microorganisms able to adapt and respond to different
environmental conditions. It is the largest genus of Actinobacteria comprising over 900 …

Abstract A-factor (2-isocapryloyl-3 R-hydroxymethyl-γ-butyrolactone) is a microbial hormone
that triggers aerial mycelium formation and secondary metabolism in Streptomyces griseus …

Bacteria transcriptional regulators are classified by their functional and sequence
similarities. Member of the TetR/AcrR family is two-domain proteins including an N-terminal …

The combination of biology and nanotechnology has led to a new generation of
nanodevices that make it possible to characterize the chemical, mechanical, and other …

In actinomycetes, the onset of secondary metabolite biosynthesis is often triggered by the
quorum-sensing signal γ-butyrolactones (GBLs) via specific binding to their cognate …

The complex morphogenesis of the bacterial genus Streptomyces has made this genus a
model prokaryote for study of multicellular differentiation, and its ability to produce a wide …