Despite aggressive multimodal treatment, glioblastoma (GBM), a grade IV primary brain
tumor, still portends a poor prognosis with a median overall survival of 12–16 months. The …

Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …

Highlights•This Clinical Practice Guideline provides management recommendations for
patients with brain metastases from solid tumours.•The guideline covers clinical and …

Hyperthermia therapy (HT) of cancer is a well-known treatment approach. With the advent of
new technologies, HT approaches are now important for the treatment of brain tumors. We …

The ability to predict heat transfer during hyperthermal and ablative techniques for cancer
treatment relies on understanding the thermal properties of biological tissue. In this work, the …

Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited
understanding of brain metastasis tumor and immune biology, drivers of resistance to …

Treating solid malignancies with chimeric antigen receptor (CAR) T cells typically results in
poor responses. Immunomodulatory biologics delivered systemically can augment the cells' …

Objective To study the role of laser interstitial thermal therapy in recurrent glioblastoma and
to assess its effect in the overall survival and in progression-free survival. Methods A …

Purpose Radiation necrosis (RN) represents a serious post-radiotherapy complication in
patients with brain metastases. Bevacizumab and laser interstitial thermal therapy (LITT) are …

Simple Summary Low-grade gliomas are slow-growing, progressive tumors of the brain that
invariably become high grade. They present a challenging entity because they can invade …