Protein phosphorylation is a post-translational modification (PTM) that orchestrates a diverse
array of cellular processes. Because this modification serves as a rapid and reversible …

The RAF‐MEK‐ERK cascade is one of the most studied signaling pathways as it controls
many vital cellular programs. There has been an immense amount of effort to determine …

OrthoVenn is a powerful web platform for the comparison and analysis of whole-genome
orthologous clusters. Here we present an updated version, OrthoVenn2, which provides new …

Exercise is essential in regulating energy metabolism and whole-body insulin sensitivity. To
explore the exercise signaling network, we undertook a global analysis of protein …

Post-translational modifications (PTMs) occur in almost all proteins and play an important
role in numerous biological processes by significantly affecting proteins' structure and …

Nowadays defying homology relationships among sequences is essential for biological
research. Within homology the analysis of orthologs sequences is of great importance for …

Exercise stimulates cellular and physiological adaptations that are associated with
widespread health benefits. To uncover conserved protein phosphorylation events …

Protein phosphorylation, one of the main protein post-translational modifications, is required
for regulating various life activities. Kinases and phosphatases that regulate protein …

The application of global “-omics” technologies to exercise has introduced new opportunities
to map the complexity and interconnectedness of biological networks underlying the tissue …

The developmentally indispensable Notch pathway exhibits a high grade of pleiotropism in
its biological output. Emerging evidence supports the notion of post-translational …