The prevalence of heart failure is increasing, and the prognosis of end-stage heart failure
remains dismal. The gold-standard therapy in end-stage heart failure remains cardiac …

In solid organ transplantation, ischemia/reperfusion (IR) injury during organ procurement,
storage and reperfusion is an unavoidable detrimental event for the graft, as it amplifies graft …

In heart transplantation, there is a lack of robust evidence of the specific causes of late
allograft failure. We hypothesized that a substantial fraction of failing heart allografts may be …

We compared efficacy and safety of tacrolimus (Tac)-based vs. cyclosporine (CyA)
microemulsion-based immunosuppression in combination with azathioprine (Aza) and …

Background. Anticytomegalovirus (CMV) prophylaxis prevents the acute disease but its
impact on subclinical infection and allograft outcome is unknown. We sought to determine …

Background—Despite improvement in short-term patient survival after heart transplantation
(HTx), long-term survival rates have not improved much, mainly because of cardiac allograft …

BACKGROUND: The utility of long-term endomyocardial biopsy surveillance in heart
transplant recipients has been questioned. This study was undertaken to identify risk factors …

BACKGROUND: Acute rejection increases the inflammatory burden of the transplanted
organ and predisposes to cardiac allograft vasculopathy (CAV). In this study we aim to …

Background—Cardiac transplantation, a procedure nearly abandoned in the 1970s, has
evolved into the standard of care for appropriate patients with end-stage heart failure. Much …

Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered
significant scientific interest in the biomedical research community owing to the unique …