Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Sonodynamic therapy and magnetic resonance-guided focused ultrasound: new therapeutic strategy in glioblastoma

L Bonosi, S Marino, UE Benigno, S Musso… - Journal of Neuro …, 2023 - Springer
Glioblastoma (GB) is one of the most aggressive and difficult-to-treat brain tumors, with a
poor prognosis and limited treatment options. In recent years, sonodynamic therapy (SDT) …

Long-acting therapeutic delivery systems for the treatment of gliomas

S Padmakumar, MM Amiji - Advanced Drug Delivery Reviews, 2023 - Elsevier
Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …

Preclinical Models and Technologies in Glioblastoma Research: Evolution, Current State, and Future Avenues

H Slika, Z Karimov, P Alimonti, T Abou-Mrad… - International journal of …, 2023 - mdpi.com
Glioblastoma is the most common malignant primary central nervous system tumor and one
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …

A phase I clinical trial of sonodynamic therapy combined with temozolomide in the treatment of recurrent glioblastoma

B Zha, J Yang, Q Dang, P Li, S Shi, J Wu, H Cui… - Journal of neuro …, 2023 - Springer
Purpose The prognosis of recurrent glioblastoma (rGBM) is poor, and there is currently no
effective treatment strategy. Sonodynamic therapy (SDT) is a new method for cancer …

Recent advances in acoustic technology in food processing

D Zadeike, R Degutyte - Foods, 2023 - mdpi.com
The development of food industry technologies and increasing the sustainability and
effectiveness of processing comprise some of the relevant objectives of EU policy …

Advancements in glioma care: focus on emerging neurosurgical techniques

M De Simone, V Conti, G Palermo, L De Maria… - Biomedicines, 2023 - mdpi.com
Background: Despite significant advances in understanding the molecular pathways of
glioma, translating this knowledge into effective long-term solutions remains a challenge …

Advanced radio frequency applicators for thermal magnetic resonance theranostics of brain tumors

N Saha, A Kuehne, JM Millward, TW Eigentler, L Starke… - Cancers, 2023 - mdpi.com
Simple Summary Localized thermal therapy has been reported to have clinical benefits as a
potent sensitizer of chemo and radiotherapy for various cancers, and for facilitating targeted …

[HTML][HTML] Current clinical investigations of focused ultrasound blood-brain barrier disruption: a review

PG Durham, A Butnariu, R Alghorazi, G Pinton… - …, 2024 - Elsevier
The blood-brain barrier (BBB) presents a formidable challenge in delivering therapeutic
agents to the central nervous system. Ultrasound-mediated BBB disruption has emerged as …

The use of histotripsy as intratumoral immunotherapy beyond tissue ablation—the rationale for exploring the immune effects of histotripsy

T Osada, X Jiang, Y Zhao, M Chen… - International Journal …, 2023 - Taylor & Francis
Mechanical high-intensity focused ultrasound (M-HIFU), which includes histotripsy, is a non-
ionizing, non-thermal ablation technology that can be delivered by noninvasive methods …