Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Cholesterol provided by low-or high-density lipoprotein is the precursor for biosynthesis of
progesterone. Once inside the cell, cholesterol can be used for steroidogenesis or esterified …

In striated muscle, the actin cytoskeleton is differentiated into myofibrils. Actin and myosin
filaments are organized in sarcomeres and specialized for producing contractile forces …

The immunoglobulin (Ig) protein domain is widespread in nature having a well-recognized
role in proteins of the immune system. In this review, we describe the proteins containing Ig …

The smooth muscle isoform of myosin light chain kinase (MLCK) is a Ca 2+-calmodulin-
activated kinase that is found in many tissues. It is particularly important for regulating …

Abnormalities in Z-disc proteins cause hypertrophic (HCM), dilated (DCM) and/or restrictive
cardiomyopathy (RCM), but disease-causing mechanisms are not fully understood …

Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can
be caused by mutations in a wide range of proteins located in different cellular …

We provide unprecedented genetic and biochemical evidence that the antiapoptotic
transcription factor STAT3 serves as a substrate for SYK tyrosine kinase both in vitro and in …

Previous research has indicated that variation in the proteome profile of longissimus
lumborum (LL) and psoas major (PM) post-rigor influences meat quality attributes such as …

In the sarcomeric M-band, the giant ruler proteins titin and obscurin, its small homologue
obscurin-like-1 (obsl1), and the myosin cross-linking protein myomesin form a ternary …