Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
[HTML][HTML] The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review
J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …
Clinical benefits and pharmacology of scutellarin: A comprehensive review
L Wang, Q Ma - Pharmacology & therapeutics, 2018 - Elsevier
Stroke and myocardial infarction are among the most common causes of mortality and
disability in the world. The ischemic injury underlying these illnesses is complex, involving …
disability in the world. The ischemic injury underlying these illnesses is complex, involving …
Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998–2018)
Alzheimer's disease (AD) is a genetically complex, progressive and irreversible
neurodegenerative disorder of the brain which involves multiple associated etiological …
neurodegenerative disorder of the brain which involves multiple associated etiological …
Therapeutic potential of naringin in neurological disorders
Neurological illnesses are multifactorial incurable debilitating disorders that may cause
neurodegeneration. These diseases influence approximately 30 million people around the …
neurodegeneration. These diseases influence approximately 30 million people around the …
[HTML][HTML] Avicenna's Canon of Medicine: a review of analgesics and anti-inflammatory substances
S Mahdizadeh, MK Ghadiri, A Gorji - Avicenna journal of …, 2015 - ncbi.nlm.nih.gov
Naturally occurring substances mentioned in medieval medical literatures currently have,
and will continue to have, a crucial place in drug discovery. Avicenna was a Persian …
and will continue to have, a crucial place in drug discovery. Avicenna was a Persian …
Multifunctional scutellarin–rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease
To discover multifunctional agents for the treatment of Alzheimer's disease (AD), a series of
scutellarein carbamate derivatives were designed and synthesized based on the multitarget …
scutellarein carbamate derivatives were designed and synthesized based on the multitarget …
Recent advances in the development of neuroprotective agents and therapeutic targets in the treatment of cerebral ischemia
Y Luo, H Tang, H Li, R Zhao, Q Huang, J Liu - European journal of …, 2019 - Elsevier
Stroke is a central nervous system disease that seriously affects people's quality of life and
has the second highest rate of morbidity and mortality in the world. At present, clinical …
has the second highest rate of morbidity and mortality in the world. At present, clinical …
Therapeutic potentials of crocin in medication of neurological disorders
Neurological sicknesses are serious, multifactorial, debilitating disorders that may cause
neurodegeneration. Neuroprotection is the protection of the structure and capacity of …
neurodegeneration. Neuroprotection is the protection of the structure and capacity of …
[HTML][HTML] Comprehensive review on the interaction between natural compounds and brain receptors: Benefits and toxicity
AR Silva, C Grosso, C Delerue-Matos… - European journal of …, 2019 - Elsevier
Given their therapeutic activity, natural products have been used in traditional medicines
throughout the centuries. The growing interest of the scientific community in …
throughout the centuries. The growing interest of the scientific community in …