Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation

S Gimondi, H Ferreira, RL Reis, NM Neves - ACS nano, 2023 - ACS Publications
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …

Mycobacterium tuberculosis infection of host cells in space and time

C Bussi, MG Gutierrez - FEMS microbiology reviews, 2019 - academic.oup.com
Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …

Recent innovations in cost-effective polymer and paper hybrid microfluidic devices

W Zhou, M Dou, SS Timilsina, F Xu, XJ Li - Lab on a Chip, 2021 - pubs.rsc.org
Hybrid microfluidic systems that are composed of multiple different types of substrates have
been recognized as a versatile and superior platform, which can draw benefits from different …

[HTML][HTML] Targeting antibiotic tolerance, pathogen by pathogen

S Meylan, IW Andrews, JJ Collins - Cell, 2018 - cell.com
Antibiotic tolerance, the capacity of genetically susceptible bacteria to survive the lethal
effects of antibiotic treatment, plays a critical and underappreciated role in the disease …

Recent advances in the analysis of single cells

L Armbrecht, PS Dittrich - Analytical chemistry, 2017 - ACS Publications
Advances of analytical methods and emerging microfluidic tools have made it possible to
investigate biological processes in living organisms in detail and reach sensitivities sufficient …

Photocatalytic nanowires‐based air filter: towards reusable protective masks

E Horváth, L Rossi, C Mercier… - Advanced functional …, 2020 - Wiley Online Library
In the last couple decades, several viral outbreaks resulting in epidemics and pandemics
with thousands of human causalities have been witnessed. The current Covid‐19 outbreak …

Recent advances in microfluidics-based cell migration research

J Ren, N Wang, P Guo, Y Fan, F Lin, J Wu - Lab on a Chip, 2022 - pubs.rsc.org
Cell migration is crucial for many biological processes, including normal development,
immune response, and tissue homeostasis and many pathological processes such as …

Investigating the composition and recruitment of the mycobacterial ImuA′–ImuB–DnaE2 mutasome

S Gessner, ZAM Martin, MA Reiche, JA Santos… - Elife, 2023 - elifesciences.org
A DNA damage-inducible mutagenic gene cassette has been implicated in the emergence
of drug resistance in Mycobacterium tuberculosis during anti-tuberculosis (TB) …

A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage response and cell-autonomous immunity to Mycobacterium …

L Raykov, M Mottet, J Nitschke, T Soldati - Elife, 2023 - elifesciences.org
Cells are perpetually challenged by pathogens, protein aggregates or chemicals, that
induce plasma membrane or endolysosomal compartments damage. This severe stress is …

Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid droplets

C Barisch, T Soldati - Biochimie, 2017 - Elsevier
Tuberculosis (Tb) is a lung infection caused by Mycobacterium tuberculosis (Mtb). With one
third of the world population latently infected, it represents the most prevalent bacterial …