Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a significant
burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is …

Saliva is a multifaceted bodily fluid that is often taken for granted but is indispensable for oral
health and overall well-being in humans. Although mainly comprised of water (99.5%) …

Medication-induced xerostomia and hyposalivation will increasingly become oral health
issues for older and geriatric patients because of the likely high prevalence of medication …

Oral homeostasis is dependent upon saliva and its content of proteins. Reflex salivary flow
occurs at a low 'resting'rate and for short periods of the day more intense taste or chewing …

Permanent damage to the salivary glands and resulting hyposalivation and xerostomia have
a substantial impact on patient health, quality of life, and healthcare costs. Currently, patients …

Identification of the specific muscarinic acetylcholine receptor (mAChR) subtypes mediating
stimulation of salivary secretion is of considerable clinical interest. Recent pharmacological …

Objectives Medication-induced salivary gland dysfunction (MISGD) causes significant
morbidity resulting in decreased quality of life. This systematic review assessed the literature …

Xerostomia, the subjective feeling of a dry mouth associated with dysfunction of the salivary
glands, is mainly caused by radiation and chemotherapy, various systemic and autoimmune …

We have recently shown that the IK1 and maxi‐K channels in parotid salivary gland acinar
cells are encoded by the KCa3. 1 and KCa1. 1 genes, respectively, and in vivo stimulated …

Patients with Sjögren's syndrome, an autoimmune disease affecting the exocrine glands,
develop salivary gland inflammation and have reduced saliva production. Similarly, saliva …