Diagnosis and management of xerostomia and hyposalivation
Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a significant
burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is …
burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is …
Saliva: An all-rounder of our body
E Roblegg, A Coughran, D Sirjani - European Journal of Pharmaceutics …, 2019 - Elsevier
Saliva is a multifaceted bodily fluid that is often taken for granted but is indispensable for oral
health and overall well-being in humans. Although mainly comprised of water (99.5%) …
health and overall well-being in humans. Although mainly comprised of water (99.5%) …
Medication-induced xerostomia and hyposalivation in the elderly: culprits, complications, and management
AG Barbe - Drugs & aging, 2018 - Springer
Medication-induced xerostomia and hyposalivation will increasingly become oral health
issues for older and geriatric patients because of the likely high prevalence of medication …
issues for older and geriatric patients because of the likely high prevalence of medication …
Regulation of salivary gland function by autonomic nerves
GB Proctor, GH Carpenter - Autonomic Neuroscience, 2007 - Elsevier
Oral homeostasis is dependent upon saliva and its content of proteins. Reflex salivary flow
occurs at a low 'resting'rate and for short periods of the day more intense taste or chewing …
occurs at a low 'resting'rate and for short periods of the day more intense taste or chewing …
Mouth-watering results: Clinical need, current approaches, and future directions for salivary gland regeneration
C Rocchi, E Emmerson - Trends in molecular medicine, 2020 - cell.com
Permanent damage to the salivary glands and resulting hyposalivation and xerostomia have
a substantial impact on patient health, quality of life, and healthcare costs. Currently, patients …
a substantial impact on patient health, quality of life, and healthcare costs. Currently, patients …
Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single-and double-knockout mice
Identification of the specific muscarinic acetylcholine receptor (mAChR) subtypes mediating
stimulation of salivary secretion is of considerable clinical interest. Recent pharmacological …
stimulation of salivary secretion is of considerable clinical interest. Recent pharmacological …
World Workshop on Oral Medicine VI: a systematic review of medication-induced salivary gland dysfunction: prevalence, diagnosis, and treatment
Objectives Medication-induced salivary gland dysfunction (MISGD) causes significant
morbidity resulting in decreased quality of life. This systematic review assessed the literature …
morbidity resulting in decreased quality of life. This systematic review assessed the literature …
Xerostomia and its cellular targets
YJ Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Xerostomia, the subjective feeling of a dry mouth associated with dysfunction of the salivary
glands, is mainly caused by radiation and chemotherapy, various systemic and autoimmune …
glands, is mainly caused by radiation and chemotherapy, various systemic and autoimmune …
Regulation of membrane potential and fluid secretion by Ca2+‐activated K+ channels in mouse submandibular glands
VG Romanenko, T Nakamoto… - The Journal of …, 2007 - Wiley Online Library
We have recently shown that the IK1 and maxi‐K channels in parotid salivary gland acinar
cells are encoded by the KCa3. 1 and KCa1. 1 genes, respectively, and in vivo stimulated …
cells are encoded by the KCa3. 1 and KCa1. 1 genes, respectively, and in vivo stimulated …
[HTML][HTML] A method for the measurement of salivary gland function in mice
H Bagavant, M Trzeciak, J Papinska… - Journal of visualized …, 2018 - ncbi.nlm.nih.gov
Patients with Sjögren's syndrome, an autoimmune disease affecting the exocrine glands,
develop salivary gland inflammation and have reduced saliva production. Similarly, saliva …
develop salivary gland inflammation and have reduced saliva production. Similarly, saliva …