Role of p53 gene in breast cancer: focus on mutation spectrum and therapeutic strategies

RP Kaur, K Vasudeva, R Kumar… - Current pharmaceutical …, 2018 - ingentaconnect.com
TP53 is a tumor suppressor gene which is commonly mutated in various cancers including
breast cancer. Alterations in the gene lead to an altered expression of various genes that are …

Breast cancer risk factors in Iran: a systematic review & meta-analysis

A Shamshirian, K Heydari, Z Shams… - … molecular biology and …, 2020 - degruyter.com
Objectives Breast cancer is known as one of the deadliest forms of cancer, and it is
increasing globally. There are a variety of proven and controversial risk factors for this …

[PDF][PDF] Quantitative analysis of p53 substitution mutation and breast cancer; An informative study in Iranian population

M Sabernezhad - Central Asian Journal of Medical and …, 2021 - academia.edu
Quantitative analysis of the p53 substitution mutation and breast cancer: An informative
study in Iranian population Page 1 8 Central Asian Journal of Medical and Pharmaceutical …

p.Arg72Pro polymorphism of P53 and breast cancer risk: a meta-analysis of case-control studies

B Diakite, Y Kassogue, G Dolo, J Wang… - BMC Medical …, 2020 - Springer
Background The effect of the p. Arg72Pro variant of the P53 gene on the risk of development
ofbreast cancer remains variable in populations. However, the use ofstrategies such …

[HTML][HTML] p53 codon 72 polymorphism and breast cancer risk: A meta-analysis

J Hou, Y Jiang, W Tang, S Jia - Experimental and …, 2013 - spandidos-publications.com
Abstract p53 is a tumor suppressor gene and plays important roles in the etiology of breast
cancer. Studies have produced conflicting results concerning the role of p53 codon 72 …

Association between the p53 polymorphisms and breast cancer risk: meta-analysis based on case–control study

XF He, J Su, Y Zhang, X Huang, Y Liu, DP Ding… - Breast cancer research …, 2011 - Springer
Abstract p53 is a tumor suppressor gene and plays an important role in the etiology of breast
cancer. However, studies on the association between p53 polymorphisms and breast cancer …

Association of the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis

ML Gonçalves, SM Borja, JABL Cordeiro, VA Saddi… - Springerplus, 2014 - Springer
This study was conducted in order to investigate the implications of the R72P polymorphism
in the TP53 gene in breast cancer risk. The enlightenment of this matter might provide a …

p. R72P, PIN3 Ins16bp polymorphisms of TP53 and CCR5Δ32 in north Indian breast cancer patients

K Guleria, S Sharma, M Manjari, MS Uppal… - Asian Pacific journal …, 2012 - koreascience.kr
Background: The present study aimed to find the prognostic implications of two
polymorphisms in TP53 (p. R72P, PIN3 Ins16bp) and one in CCR5 ($ CCR5 {\Delta} 32$) in …

TP53 polymorphisms in sporadic North Indian breast cancer patients

S Sharma, V Sambyal, K Guleria… - Asian Pacific Journal …, 2014 - koreascience.kr
Background: The purpose of this study was to evaluate the potential association of five (p.
P47S, p. R72P, PIN3 Ins16bp, p. R213R and r. 13494g> a) polymorphisms of TP53 with the …

1 267 例乳腺癌临床与免疫组化指标的相关性分析

刘红艳, 宋丰举, 雷蕾, 郑红, 李海欣, 陈可欣 - 中国肿瘤临床, 2011 - cjco.cn
分析乳腺浸润性导管癌的临床特征及6 种免疫组化指标表达的关系, 探讨其临床意义. 方法:
采用免疫组化SP 法对1 267 例乳腺癌患者的术后肿瘤石蜡标本进行ER, PR, C-erbB-2, P53, Ki …