[HTML][HTML] Unveiling Tumorigenesis Mechanisms and Drug Therapy in Neuroblastoma by Mass Spectrometry Based Proteomics
K Ren, Y Wang, M Zhang, T Tao, Z Sun - Children, 2024 - mdpi.com
Neuroblastoma (NB) is the most common type of extracranial solid tumors in children.
Despite the advancements in treatment strategies over the past years, the overall survival …
Despite the advancements in treatment strategies over the past years, the overall survival …
In-vitro and in-vivo studies of two-drug cocktail therapy targeting chemobrain via the Nrf2/NF-κB signaling pathway
Today, we critically need alternative therapeutic options for chemotherapy-induced cognitive
impairment (CICI), often known as chemo brain. Mitochondrial dysfunction and oxidative …
impairment (CICI), often known as chemo brain. Mitochondrial dysfunction and oxidative …
Studies on N-(6-Indazolyl) benzenesulfonamide Derivatives as Potential Anticancer Agents: Integrating Synthesis, In silico Docking, and Molecular Dynamics …
A new series of benzenesulfonamide derivatives, namely N-(1-(2-chloropyrimidin-4-yl)-1H-
indazol-5-yl) compounds (4a-i) and N-(1-(2-chloropyrimidin-4-yl)-6-ethoxy-1H-indazol-5-yl) …
indazol-5-yl) compounds (4a-i) and N-(1-(2-chloropyrimidin-4-yl)-6-ethoxy-1H-indazol-5-yl) …
3, 5-Disubstituted-thiazolidine-2, 4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation
Diabetes is one of the fastest-growing metabolic disorders, nearly doubling the number of
patients each year. There are different treatment approaches available for the management …
patients each year. There are different treatment approaches available for the management …
Targeting inflammation through inhibition of COX-2 by substituted 4-thiazolidinone analogues: in-vitro, in-vivo and in-silico studies
The prolonged or chronic use of anti-inflammatory agents that are being used clinically is
highly unsafe. This flaw or disadvantage has motivated scientists to create new heterocyclic …
highly unsafe. This flaw or disadvantage has motivated scientists to create new heterocyclic …
Thiazolidine-2, 4-dione hybrids as dual alpha-amylase and alpha-glucosidase inhibitors: design, synthesis, in vitro and in vivo anti-diabetic evaluation
Twelve 3, 5-disubstituted-thiazolidine-2, 4-dione (TZD) hybrids were synthesized using
solution phase chemistry. Continuing our previous work, nine O-modified ethyl vanillin (8a–i) …
solution phase chemistry. Continuing our previous work, nine O-modified ethyl vanillin (8a–i) …
Molecular insights into epoxyazadiradione induced death in triple-negative breast cancer cells: A system biology approach
S Lakshmi, S Priya - Gene, 2024 - Elsevier
Epoxyazadiradione is an important limonoid with immense pharmacological potential. We
have reported previously that epoxyazadiradione (EAD) induces apoptosis in triple negative …
have reported previously that epoxyazadiradione (EAD) induces apoptosis in triple negative …
[引用][C] Exploring 5-Nitro-N-phenyl-3-(phenylamino)-1H-indazole-1-carboxamide (5-NPIC) Derivatives as Anticancer Agents: Synthesis, Docking, and Molecular …
The synthesis and characterization of a series of 5-nitro-N-phenyl-3-(phenylamino)-1H-
indazole-1-carboxamide 5-NPIC derivatives (5a-5v) were reported as anticancer agents in …
indazole-1-carboxamide 5-NPIC derivatives (5a-5v) were reported as anticancer agents in …