The biomechanics of induction in adolescent idiopathic scoliosis: theoretical factors
JF Sarwark, RM Castelein, A Maqsood, CE Aubin - JBJS, 2019 - journals.lww.com
Adolescent idiopathic scoliosis (AIS) is a common clinical condition that develops around
puberty, has implications for the rest of oneLs life, and is a classic enigma in orthopaedics …
puberty, has implications for the rest of oneLs life, and is a classic enigma in orthopaedics …
Role of primary cilia in skeletal disorders
Primary cilia are highly conserved microtubule‐based organelles that project from the cell
surface into the extracellular environment and play important roles in mechanosensation …
surface into the extracellular environment and play important roles in mechanosensation …
Ependymal polarity defects coupled with disorganized ciliary beating drive abnormal cerebrospinal fluid flow and spine curvature in zebrafish
H Xie, Y Kang, J Liu, M Huang, Z Dai, J Shi, S Wang… - Plos …, 2023 - journals.plos.org
Idiopathic scoliosis (IS) is the most common spinal deformity diagnosed in childhood or early
adolescence, while the underlying pathogenesis of this serious condition remains largely …
adolescence, while the underlying pathogenesis of this serious condition remains largely …
Idiopathic scoliosis as a rotatory decompensation of the spine
Many years of dedicated research into the etiology of idiopathic scoliosis have not led to one
unified theory. We propose that scoliosis is a mechanical, rotatory decompensation of the …
unified theory. We propose that scoliosis is a mechanical, rotatory decompensation of the …
Growth and nutritional status, and their association with lung function: a study from the international Primary Ciliary Dyskinesia Cohort
Chronic respiratory disease can affect growth and nutrition, which can influence lung
function. We investigated height, body mass index (BMI), and lung function in patients with …
function. We investigated height, body mass index (BMI), and lung function in patients with …
Why, when and how to investigate primary ciliary dyskinesia in adult patients with bronchiectasis
M Contarini, A Shoemark, J Rademacher… - Multidisciplinary …, 2018 - Springer
Bronchiectasis represents the final pathway of several infectious, genetic, immunologic or
allergic disorders. Accurate and prompt identification of the underlying cause is a key …
allergic disorders. Accurate and prompt identification of the underlying cause is a key …
[HTML][HTML] The axonemal dynein heavy chain 10 gene is essential for monocilia motility and spine alignment in zebrafish
Adolescent idiopathic scoliosis (AIS) is a common pediatric musculoskeletal disorder
worldwide, characterized by atypical spine curvatures in otherwise healthy children. Human …
worldwide, characterized by atypical spine curvatures in otherwise healthy children. Human …
Identification of Two Novel DNAAF2 Variants in Two Consanguineous Families with Primary Ciliary Dyskinesia
C Lu, D Yang, C Lei, R Wang, T Guo… - Pharmacogenomics and …, 2021 - Taylor & Francis
Background Dynein axonemal assembly factor 2 (DNAAF2) is involved in the early
preassembly of dynein in the cytoplasm, which is essential for motile cilia function. Primary …
preassembly of dynein in the cytoplasm, which is essential for motile cilia function. Primary …
Idiopathic scoliosis families highlight actin-based and microtubule-based cellular projections and extracellular matrix in disease etiology
EE Baschal, EA Terhune, CI Wethey… - G3: Genes …, 2018 - academic.oup.com
Idiopathic scoliosis (IS) is a structural lateral spinal curvature of≥ 10° that affects up to 3% of
otherwise healthy children and can lead to life-long problems in severe cases. It is well …
otherwise healthy children and can lead to life-long problems in severe cases. It is well …
[HTML][HTML] Aetiological process of idiopathic scoliosis: From a normal growing spine into a complex 3D spinal deformity
TPC Schlösser, AI Tsirikos, RM Castelein - Orthopaedics and Trauma, 2021 - Elsevier
In more than a century of dedicated research into its aetio-pathogenesis, many attempts
have been made to understand the exact cause of idiopathic scoliosis. In the literature, the …
have been made to understand the exact cause of idiopathic scoliosis. In the literature, the …