The main challenges associated with leishmaniasis chemotherapy are drug toxicity, the
possible emergence of resistant parasites, and a limited choice of therapeutic agents …

Objective The aim of this study was to delineate the mechanisms of action of the plant
Eucalyptus citriodora used traditionally for the treatment of type 2 diabetes. Methods Insulin …

Natural products represent a source of biologically active molecules that have an important
role in drug discovery. The aromatic plant Blepharocalyx salicifolius has a diverse chemical …

Objective This study aimed to demonstrate the mechanistic basis of Heritiera fomes, which
has traditionally been used to treat diabetes. Methods Clonal pancreatic β-cells and primary …

This work aimed to evaluate the chemical composition, yield, and antifungal activity of the
essential oils (EO) of native species from the 'Campos de Cima da Serra'region, South …

Os polifenóis são um grupo de metabólitos secundários vegetais que possuem uma
variedade de bioatividades conhecidas, dentre elas a capacidade de funcionar como …

Chalcone derivatives afford several pharmacological activities. However, a general synthetic
method for 2', 4'‐dihydroxy‐6'‐methoxy‐3', 5'‐dimethylchalcone (DMC) derivatives has not …

The loss of leaves by plant species found in the Cerrado (Brazilian savanna) is an
energetically expensive process due to adverse environmental conditions and predation by …

La composición química del aceite esencial obtenido por destilación al vapor de las hojas
frescas de Blepharocalyx salicifolius (Kunth) O. Berg (Myrtaceae) se analizó por CG/EM …

Natural products have been used in traditional medicine throughout history. All drugs and
medicinal agents were derived from natural substances or inspired by a natural product. The …